CBSE Class 12 Biology Reproduction In Human Beings Worksheet Set A

Read and download the CBSE Class 12 Biology Reproduction In Human Beings Worksheet Set A in PDF format. We have provided exhaustive and printable Class 12 Biology worksheets for Chapter 2 Human Reproduction, designed by expert teachers. These resources align with the 2025-26 syllabus and examination patterns issued by NCERT, CBSE, and KVS, helping students master all important chapter topics.

Chapter-wise Worksheet for Class 12 Biology Chapter 2 Human Reproduction

Students of Class 12 should use this Biology practice paper to check their understanding of Chapter 2 Human Reproduction as it includes essential problems and detailed solutions. Regular self-testing with these will help you achieve higher marks in your school tests and final examinations.

Class 12 Biology Chapter 2 Human Reproduction Worksheet with Answers

Question. Which of the following hormones is not secreted by human placenta?
(a) hCG
(b) Estrogens
(c) Progesterone
(d) LH

Answer: D

Question. Immediately after ovulation, the mammalian egg is covered by a membrane known as
(a) chorion
(b) zona pellucida
(c) corona radiata
(d) vitelline membrane.

Answer: C

Question. Which part of the sperm plays an important role in penetrating the egg membrane?
(a) Allosome
(b) Tail
(c) Autosome
(d) Acrosome

Answer: D

Question. The nutritive cells found in seminiferous tubules are
(a) Leydig’s cells
(b) atretic follicular cells
(c) Sertoli cells
(d) chromaffin cells.

Answer: C

Question. Sertoli cells are regulated by the pituitary hormone known as
(a) LH
(b) FSH
(c) GH
(d) prolactin.

Answer: B

Question. Ovulation in the human female normally takes place during the menstrual cycle
(a) at the mid secretory phase
(b) just before the end of the secretory phase
(c) at the beginning of the proliferative phase
(d) at the end of the proliferative phase.

Answer: D

Question. At what stage of life is oogenesis initiated in a human female?
(a) At puberty
(b) During menarche
(c) During menopause
(d) During embryonic development

Answer: D

Question. Which among the following has 23 chromosomes?
(a) Spermatogonia
(b) Zygote
(c) Secondary oocyte
(d) Oogonia

Answer: C

Question. Delivery of developed foetus is scientifically called
(a) parturition
(b) oviposition
(c) abortion
(d) ovulation.

Answer: A

Question. After ovulation Graafian follicle regresses into
(a) corpus atresia
(b) corpus callosum
(c) corpus luteum
(d) corpus albicans

Answer: C

Question. In human adult females oxytocin
(a) stimulates pituitary to secrete vasopressin
(b) causes strong uterine contractions during parturition
(c) is secreted by anterior pituitary
(d) stimulates growth of mammary glands.

Answer: B

Assertion Reason Question:

a. Both assertion and reason are true, and reason is the correct explanation of assertion
b. Both assertion and reason are true, but reason is not the correct explanation of assertion
c. Assertion is true but reason is false
d. Both assertion and reason are false.

Question. Assertion: Colostrum produced in first 2-3 days after parturition is rich in nutrients.
Reason: placenta induces the signals for expulsion of the fully developed.

Answer: B

Question. Assertion: All sperms released at a time do not fertilise the ovum.
Reason: Fertilisation occur only when ovum and sperm fuse at the ampullary-isthmic junction.

Answer: B

Question. Assertion: The endometrium undergoes cyclic changes during the menstrual cycle.
Reason: Perimetrium contracts strongly during delivery of the baby.

Answer: C

Question. Assertion: The middle piece of the sperm is called is powerhouse.
Reason: Numerous mitochondria in the middle piece produce energy for the movement of the tail.

Answer: A

Question. Assertion: the female gamete is produced at the time of puberty.
Reason: gonadotropin releasing hormone controls the process of oogenesis.

Answer: D

Question. Assertion: Signals for parturition originate from placenta and the developed foetus.
Reason: Relaxin is released by the placenta.

Answer: B

Question. Assertion: The embryo with 8 to 16 blastomeres is called a morula.
Reason: The morula continuously divides to transform into trophoblast.

Answer: C

Question. Assertion: The uterus is shaped like an inverted pear.
Reason: The inner glandular layer lining the uterine cavity is called as myometrium.

Answer: C

Question. Assertion: the fertilized egg contains 23 pairs of chromosomes
Reason: zygote is formed by the fusion of egg and the sperm.

Answer: A

Short Answer type Questions:

Question. What is pregnancy hormone? Why is it so called? Name two sources of this hormone in a human female.
Answer: Human chorionic gonadotropin(hcG) chorionic thyrotropin, chorionic corticotropin and relaxin are secreted by placenta. The hcG stimulates and maintains the corpus luteum to secrete progesterone. Progesterone maintains endometrium throughout the pregnancy. These hormones are associated with pregnancy and therefore known as pregnancy hormone.

Question. What is the role of following hormones in the female reproductive cycle:
1) FSH
2) LH
3) Progesterone
Answer: 1.FSH- Stimulates growth of Graafian follicle and maturation of ovum in it. Stimulates secretion of estrogen from follicle cells.
2.LH- Stimulates ovulation and induces the formation of corpus luteum. Stimulates secretion of progesterone from corpus luteum.
3.Progesterone- brings about uterine growth, facilitates the implantation of embryos and formation of the placenta. Prevents other Graafian follicles from maturing.

Question. State the fate of the trophoblast of a human blastocyst at the time of implantation and that of the inner cell mass immediately after implantation.
Answer: The trophoblast layer of the human blastocyst gets attached to the endometrium and the inner cell mass gets differentiated into an embryo. After attachment, the uterine cells divide rapidly and cover the blastocyst. As a result, the blastocyst becomes embedded in the endometrium of the uterus. It is termed Implantation.

Question. Name the hormone which stimulates the secretion of ovarian hormones. What would happen if the blood concentration of ovarian hormones increases?
Answer: FSH and LH stimulate the ovarian hormones. A feedback system becomes operative when the level of estrogen increases. The anterior pituitary is inhibited from secreting FSH and stimulated to secrete LH.

Question. Differentiate between spermiogenesis and spermiation.
Answer: Difference between spermiogenesis and Spermiation: Spermiogenesis is the process of transformation of non-motile spermatids into mature motile sperms (male-gametes) whereas speciation is the release of sperms from Sertoli cells of seminiferous tubules.

Question. a) In which part of the human female reproductive system do the following events take place.
I. Release of 1st polar body
II. Release of 2nd polar body
III. Fertilization
IV. Implantation
b) From where do the signals for parturition originate and what does maternal pituitary release for stimulating uterine contractions for childbirth.
Answer: a) I) Ovary II) In the isthmus- ampullary junction of fallopian tube III) Isthmus- ampullary junction of fallopian tube. IV) In the uterus
b) Fully developed foetus and placenta, oxytocin

Question. At what stage of life is oogenesis initiated in a human female? When does the oocyte complete oogenesis?
Answer: Embryonic life. When the sperm enters the egg.

Question. Define spermatogenesis. Where does it occur?
Answer: The transformation of non-motile spermatids into motile spermatozoa is called spermiogenesis. It occurs inside seminiferous tubules of testes.

Question. Give a scientific term for the following:
a) Layer of follicle cells that envelops the egg outside the zona pellucida.(a). Ans. corona radiata
b) The finger-like projection appearing on the trophoblast after implantation.
Answer: (a) corona radiata (b) Chorionic villi

Question. How does colostrum provide initial protection against diseases to new born infants? Give one reason.
Answer: The colostrum provides antibodies that are essential to developing resistance for new born babies.

Question. Explain the formation of placenta after implantation in a human female.
Answer: Trophoblast forms finger -like projections called chorionic villi that are surrounded by uterine tissue and maternal blood. The chorionic villi and uterine tissue become interdigitated with each other to form placenta.

Question. What is ovulation? What happens to the Graafian follicle after ovulation?
Answer: Ovulation: The release of eggs (at secondary oocyte stage) after rupturing of Graafian follicle is called ovulation. After the ovulation, the granulosa cells as well as the stroma cells from theca Interna rapidly multiply to fill the cavity of the Graafian follicle which becomes the corpus luteum. If fertilization occurs, the corpus luteum grows further and secretes hormones. If fertilization does not take place, the corpus luteum regresses and forms a yellow body.

Question. a) How many lobules are found in each testis?
b) What is the function of Bulbourethral glands?
Answer: (a) 250 (b) Secretion of alkaline fluid. They also secrete mucus that lubricates the end of the penis and the lining of the urethra.

Question. Write the location and functions of Sertoli cells in humans?
Answer: Sertoli cells. These are present in the seminiferous tubules of the testis. They provide nutrition to germ cells. They play a vital role in the maturation of spermatids into motile sperms.

Long Answer Type Questions:

Question. Describe the roles of pituitary and ovarian hormones during the menstrual cycle in a human female.
Answer: The cycle of events starting from one menstruation till next in female primates is called menstrual cycle. It comprises of four phases which are regulated by both pituitary (LH and FSH) and ovarian (oestrogen and progesterone) hormones that affect ovaries and uterus, respectively. The events occurring in a menstrual cycle are as follows
Menstrual phase (from 3rd-5th day in a 28-day cycle) Initiated by reduced secretion of LH, progesterone and oestrogen. The endometrium breaks down and blood along with unfertilised ovum constitutes menstrual flow.
Follicular phase (from 6th-13th day in a 28-day cycle) The FSH (Follicle Stimulating Hormone) secreted by anterior pituitary stimulates ovarian follicle to secrete oestrogens. These oestrogens stimulate proliferation of uterine walls as a result of which endometrium gets thickened (due to rapid cell division and increase in uterine glands and blood vessels).
Ovulatory phase (14th day in 28-day cycle) -Pituitary hormones, i.e. LH and FSH reach the highest level in middle of the cycle. Rapid secretion of LH causes ovulation thus, inducing the rupture of Graafian follicle to release secondary oocyte and a polar body.
Luteal or secretory phase (from 15th-28th day in a 28-day cycle) The pituitary hormone LH stimulates the remaining cells of ovarian follicles to develop into corpus luteum. This corpus
luteum secretes large amount of progesterone and maintains endometrium thickening for the implantation of fertilised ovum during pregnancy. In the absence of fertilisation, the hormone levels are reduced (LH and progesterone) and endometrium disintegrates leading to onset of another menstrual cycle.

Question. Explain in detail the various developmental stages of the zygote until implantation with suitable diagrams.
Answer: When the zygote moves through the isthmus of the oviduct, the mitotic division is initiated and is called the cleavage towards the uterus to form 2,4,8,16 daughter cells called blastomeres. It is an embryo containing 8 to 16 blastomeres from the morula. It continues to transform and divide into blastocysts as it further approaches the uterus. In the blastocyst, the blastomeres are organized into an outer layer referred to as the trophoblast and the inner cell mass, which is an inner collection of cells attached to the trophoblast. This layer gets attached to the endometrium and the inner cell mass transforms into the embryo. After attachment, the cells of the uterus rapidly divide and covers up the entire blastocyst. This causes the blastocyst to implant in the endometrium of the uterus which leads to conception. 
CBSE Class 12 Biology Reproduction In Human Beings Worksheet

Question. What is spermatogenesis? Briefly describe the process of spermatogenesis.
Answer: Spermatogenesis. The process of sperm formation from the sperm mother cells of testis (male gonad) is called spermatogenesis. It is completed in four phases, viz. spermatocytogenesis, meiosis I, meiosis II, and spermiogenesis. Spermatocytogenesis, Meiosis I and Meiosis II. The sperms are formed from the sperm mother cells present in the germinal layer of seminiferous tubules of the testis. Some of the mother cells enlarge to divide mitotically to form spermatogonia.
Growth phase: Some of them enter a period of growth and are called primary spermatocytes which are diploid.
Maturation phase: These cells divide meiotically to form two haploid secondary spermatocytes. Each secondary spermatocyte again divides mitotically. Thus, one primary spermatocyte forms haploid spermatids.
Spermiogenesis: These develop into complete spermatozoan. These possess head which is embedded in the nourishing cells called Sertoli cells. The process of conversion of spermatid into spermatozoan is called spermiogenesis.

Question. Briefly describe the process of oogenesis.
Answer:
CBSE Class 12 Biology Reproduction In Human Beings Worksheet

Diagram based/case based/passage-based questions
 

Question. 
CBSE Class 12 Biology Reproduction In Human Beings Worksheet

Study the figure given and answer the questions that follows:

Question. Pick out and name the cells that undergo spermiogenesis.
(a) Spermatogonia undergo spermiogenesis
(b) Spermatids undergo spermiogenesis
(c) Secondary spermatocytes undergo spermiogenesis
(d) Primary spermatocytes undergo spermiogenesis.

Answer: B

Question. How many sperms will be produced from 50 primary spermatocytes?
(a) 400 sperms
(b) 1000 sperms
(c) 200sperms
(d) 100sperms

Answer: C

Question. Testosterone is secreted which cell:
(a) Sertoli cell
(b) Spermatids
(c) Leydig cells
(d) Spermatogonia

Answer: C

Question. The function of Sertoli cell is:
(a) Nutrition to the sperms
(b) Nutrition to the Leydig cell
(c) Nutrition to the basal lamina
(d) Excretion from sperm

Answer: A

Question. Cross section of testes shows:
(a) Seminiferous tubules with different stages of development of sperm
(b) Development of Sertoli cells
(c) Many testicular lobules
(d) Many spermatogonia

Answer: A

Question. 
CBSE Class 12 Biology Reproduction In Human Beings Worksheet
Study the graph given and answer any four questions:

Question. What are the three phases of oogenesis?
(a) Multiplication phase, growth phase and reproductive phase
(b) Multiplication phase, growth phase and maturation phase
(c) Growth phase, maturation phase and secretory phase
(d) Secretory phase, growth phase and maturation phase

Answer: B

Question. The phase in woman’s life when ovulation and menstruation stops is called:
(a) Menarche
(b) Puberty
(c) Menopause
(d) Reproduction

Answer: C

Question. Withdrawing of which hormone causes menstruation?
(a) Estrogen
(b) Progesterone
(c) FSH
(d) LH

Answer: B

Question. Name the ovarian and pituitary hormones that are responsible for development of follicles.
(a) Estrogen and LH
(b) Estrogen and progesterone
(c) FSH and LH
(d) Progesterone and FSH

Answer: A

Question. In which phase of menstrual cycle corpus luteum is formed and names the hormone it secretes.
(a) Ovulatory phase and progesterone
(b) Luteal phase and progesterone
(c) Follicular phase and progesterone
(d) Menstrual phase and progesterone

Answer: B

Question. 
CBSE Class 12 Biology Reproduction In Human Beings Worksheet

Question. Which layer gets attached to the cells of endometrium and names the part which develops into embryo?
(a) Trophoblast and inner cell mass
(b) Trophoblast and ectoderm
(c) Ectoderm and endoderm
(d) Trophoblast and mesoderm

Answer: A

Question. How is the placenta connected to the embryo?
(a) By chorionic villi
(b) By umbilical cord
(c) By inner layer
(d) By trophoblast

Answer: B

Question. Name the stage of human embryo the figure represents.
(a) Gastrula
(b) Blastocyst
(c) Oocyte
(d) Primary oocyte

Answer: B

Question. Where are the stem cells located in this embryo?
(a) Inner cell mass
(b) Blastocoel
(c) Blastomeres
(d) Blastocyst

Answer: A

Question. Write the name of “a”
(a) Blastomere
(b) Trophoblast
(c) Morula
(d) Gastrula

Answer: B

 

1 a) When and how does placenta develop in human female?

b) How is the placenta connected to the embryo?

c) Placenta acts as an endocrine gland. Explain.

2 Explain the different stages of Oogenesis in humans starting from foetal life till its completion. When and where in the body is oogenesis completed?

3 Describe the process of spermatogenesis. Where does it occur in human male?

4 Trace the development of zygote till implantation.

5 Represent diagrammatically spermatogenesis and oogenesis. 

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CBSE Biology Class 12 Chapter 2 Human Reproduction Worksheet

Students can use the practice questions and answers provided above for Chapter 2 Human Reproduction to prepare for their upcoming school tests. This resource is designed by expert teachers as per the latest 2026 syllabus released by CBSE for Class 12. We suggest that Class 12 students solve these questions daily for a strong foundation in Biology.

Chapter 2 Human Reproduction Solutions & NCERT Alignment

Our expert teachers have referred to the latest NCERT book for Class 12 Biology to create these exercises. After solving the questions you should compare your answers with our detailed solutions as they have been designed by expert teachers. You will understand the correct way to write answers for the CBSE exams. You can also see above MCQ questions for Biology to cover every important topic in the chapter.

Class 12 Exam Preparation Strategy

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