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Principles of Inheritance and Variation MCQ Questions with Answers Class 12 Biology
Question- The monohybrid genotypic ratio 1 : 2 : 1 in F2 generation indicates
(b) independent assortment
(d) incomplete dominance
Question- The distance between the genes is measured by
(b) map unit
(c) Dobson unit
Question- In a dihybrid cross, F2 phenotypic ratio is 13 : 3. It is case of
(a) complementary genes
(b) epistatic genes
(c) multigenic inheritance
(d) incomplete dominance
Question- In sickle-cell anaemia, shape of RBCs under oxygen tension becomes
(a) biconcave disc like
(b) elongated and curved
Question- Linkage reduces the frequency of
(b) all parental types.
(c) homozygous recessive parents.
(d) heterozygous recessive parents.
Question- In XO type of sex determination
(a) females produce two different types of gametes.
(b) males produce two different types of gametes.
(c) females produce gametes with Y chromosomes.
(d) males produce single type of gametes.
Question- HbA and HbS alleles of normal and sickle celled RBC are
(a) dominant-recessive alleles.
(b) polygenic alleles.
(c) codominant alleles.
(d) multiple alleles.
Question- The ‘X’ body of Henking was observed in
(a) all sperms during spermatogenesis.
(b) all eggs during oogenesis.
(c) half of the sperms during spermatogenesis.
(d) half of the eggs during oogenesis.
Question- The test cross is used to determine the
(a) genotype of the plant
(b) phenotype of the plant
(c) both (a) and (b)
(d) None of the above
Question- Sickle cell anaemia is
(a) caused by substitution of valine by glutamic acid in the beta globin chain of haemoglobin.
(b) caused by a change in a single base pair of DNA.
(c ) characterized by elongated sickle like RBCs with a nucleus.
(d) an autosomal linked dominant trait.
Question- The contrasting pairs of factors in Mendelian crosses are called
(a) multiple alleles
Question- Mental retardation in man associated with sex chromosomal abnormality is usually due to
(a) increase in size of X-chromosome.
(b) increase in size of Y-chromosome.
(c) increase in number of Y-chromosome.
(d) increase in number of X-chromosome.
Question- Which of the following crosses will give tall and dwarf pea plants in same proportions?
(a) TT × tt
(b) Tt × tt
(c) TT × Tt
(d) tt × tt
Question- The F2 generation of a cross produced identical phenotypic and genotypic ratio. It is not an expected Mendelian result, and can be attributed to
(a) independent assortment
(c) incomplete dominance
(d) none of the above
1.Name one autosomal dominant and one autosomal recessive Mendelian disorder in humans.
2.Write the genotype of i) an individual who is carrier of sickle cell anaemia gene but apparently unaffected, and ii) an individual affected with the disease.
3.A human being suffering from Down’s syndrome shows trisomy of 21st chromosome. Mention the cause of this chromosomal abnormality.
4.Write the percentage of F2 homozygous and heterozygous populations in a typical monohybrid cross.
5.A man with blood group A married a woman with B group. They have a son with AB blood group and a daughter with blood group O. Workout the cross and show the possibility of such inheritance.
6.The male fruit fly and female fowl are heterogametic while the female fruit fly and male fowl are homogametic. Why are they called so?
7.A plant of Antirrhinum majus with red flowers was crossed with another plant of the same species with white flowers. The plants of the F1 generation bore pink flowers. Explain the pattern of inheritance with the help of a cross.
8.A woman with blood group ‘O’ married a man with AB group. Show the possible blood groups of the progeny. List the alleles involved in this inheritance.
9.How does a test cross help in identifying the genotype of the organism? Explain.
10.When a tall pea plant was selfed, it produced one fourth of its progeny as dwarf. Explain with the help of a cross.
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