CBSE Class 11 Biology Breathing And Exchange of Gases Worksheet Set A

Breathing And Exchange of Gases

Respiration is the oxidation of nutrients in the living cells to release energy for biological work.

Breathing is the exchange of O₂ from the atmosphere with CO₂ produced by the cells.

♦ RESPIRATORY ORGANS

• General body surface: E.g. lower invertebrates like sponges, coelenterates, flatworms etc.
• Skin or moist cuticle (cutaneous respiration): E.g. earthworms, leech, amphibians etc.
• Tracheal tubes: E.g. insects, centipede, millipede, spider.
• Gills (Branchial respiration): E.g. fishes, tadpoles, prawn.
• Lungs (Pulmonary respiration): E.g. most vertebrates.

HUMAN RESPIRATORY SYSTEM

It consists of a pair of air passages (air tract) and lungs.

1. Air passages

- Conducting part which transports the atmospheric air into the alveoli, clears it from foreign particles, humidifies and brings the air to body temperature.
External nostrils → nasal passage → nasal chamber (cavity) → nasopharynx (a part of pharynx) → glottis → larynx → trachea → primary bronchi → secondary bronchi → tertiary bronchi → bronchioles → terminal bronchioles → respiratory bronchiole → alveolar duct.

- Each terminal bronchiole gives rise to a number of very thin and vascularised alveoli (in lungs).
- A cartilaginous Larynx (sound box or voice box) helps in sound production.
- During swallowing, epiglottis (a thin elastic cartilaginous flap) closes glottis to prevent entry of food into larynx.
- Trachea, all bronchi and initial bronchioles are supported by incomplete cartilaginous half rings.

2. Lungs

- Situate in thoracic chamber and rest on diaphragm.
- Right lung has 3 lobes and left lung has 2 lobes.
- Lungs are covered by double-layered pleura (outer parietal pleura and inner visceral pleura).
- The pleural fluid present in between these 2 layers lubricates the surface of the lungs and prevents friction between the membranes.
- Lungs= Bronchi + bronchioles + alveoli.
- Alveoli and their ducts form the respiratory or exchange part of the respiratory system.
- Alveoli are the structural and functional units of lungs.

Steps of respiration

1. Pulmonary ventilation (breathing).
2. Gas exchange between alveoli & blood.
3. Gas transport (O₂ transport & CO₂ transport).
4. Gas exchange between blood & tissues.
5. Cellular or tissue respiration.

MECHANISM OF BREATHING (INSPIRATION & EXPIRATION)

a. Inspiration

- Active intake of air from atmosphere into lungs.
- During this, the diaphragm contracts (flattens) causing an increase in vertical volume (antero-posterior axis).
- Contraction of external intercostal muscles (muscles found between ribs) lifts up the ribs and sternum causing an increase in thoracic volume in the dorso-ventral axis.
- These changes reduce pressure inside the thorax causing the expansion of lungs. Thus pulmonary volume increases resulting in decrease of intra-pulmonary pressure to less than the atmospheric pressure. So air moves into lungs.

b. Expiration

- Passive expelling of air from the lungs.
- During this, intercostal muscles & diaphragm relax causing a decrease in thoracic volume and thereby pulmonary volume. So air moves out.
- During forceful expiration, abdominal muscles and internal inter-costal muscles contract.

Respiratory volumes and capacities

• Tidal volume (TV): Volume of air inspired or expired during a normal respiration. It is about 500 ml. i.e., 6000- 8000 ml per minute.
• Inspiratory reserve volume (IRV) or complemental

air: Additional volume of air that can inspire by forceful inspiration. It is 2500-3000 ml.

• Expiratory reserve volume (ERV) or supplemental

air: Additional volume of air that can expire by a forceful expiration. It is 1000-1100 ml.

• Residual volume (RV): Volume of air remaining in lungs after a forcible expiration. It is 1100-1200 ml.
• Inspiratory capacity (IC): Total volume of air inspired after a normal expiration (TV + IRV). It is 3000-3500 ml.
• Expiratory capacity (EC): Total volume of air expired after a normal inspiration (TV + ERV). It is 1500-1600 ml.
• Functional residual capacity (FRC): Volume of air remaining in the lungs after a normal expiration (ERV + RV). It is 2100-2300 ml.
• Vital capacity (VC): Volume of air that can breathe in after a forced expiration or Volume of air that can breathe out after a forced inspiration (ERV + TV + IRV). It is 3500-4500 ml.
• Total lung capacity (TLC): Total volume of air in the lungs after a maximum inspiration. (RV + ERV + TV + IRV or VC + RV). It is 5000-6000 ml.
• Part of respiratory tract (from nostrils to terminal bronchi) not involved in gaseous exchange is called dead space. Dead air volume is about 150 ml.

- Respiratory cycle= an inspiration + an expiration
- Normal respiratory (breathing) rate: 12-16 times/min
- Spirometer (respirometer): To measure respiratory rate.

GAS EXCHANGE

Gas exchange occurs between

1. Alveoli and blood       2. Blood and tissues

Alveoli are the primary sites of gas exchange. O₂ & CO₂ are exchanged by simple diffusion. It depends upon the following factors:

• Pressure/ concentration gradient: The Partial pressures (individual pressure of a gas in a gas mixture) of O₂ and CO₂ (pO₂ and pCO₂) are given below.

pO₂ in alveoli is more (104 mm Hg) than that in the blood capillaries (40 mm Hg). So O₂ diffuses into capillary blood. pCO₂ in deoxygenated blood is more (45 mm Hg) than that in the alveolus (40 mm Hg). So CO₂ diffuses to alveolus.

• Solubility of gases: Solubility of CO₂ is 20-25 times higher than that of O₂. So the amount of CO₂ that can diffuse through the diffusion membrane per unit difference in partial pressure is higher than that of O₂.

• Thickness of membranes: The diffusion membrane is made up of 3 layers:

a) Thin squamous epithelium of alveoli

b) Endothelium of alveolar capillaries

c) Basement substance between them.

Its total thickness is only 0.5 µm. It enables easy gas exchange.

• Surface area: Presence of alveoli increases the surface area of lungs. It increases the gas exchange.

GAS TRANSPORT (O₂ TRANSPORT & CO₂ TRANSPORT)

It is the transport of respiratory gases (O₂ & CO₂) from alveoli to the systemic tissues and vice versa.

1. O₂ TRANSPORT

It is the transport of O2 from lungs to various tissues.

It occurs in 2 ways:

a. In physical solution (blood plasma): About 3% of O₂ is carried in a dissolved state through plasma.

b. As oxyhaemoglobin: About 97% of O₂ is transported by RBC. O₂ binds with haemoglobin (red coloured iron containing pigment present in the RBCs) to form oxyhaemoglobin. This is called oxygenation. Hb has 4 haem units. So each Hb molecule can carry 4 oxygen molecules. Binding of O2 depends upon pO₂, pCO₂, H⁺ ion concentration (pH) and temperature.

- In the alveoli, high pO₂, low pCO₂, lesser H⁺ ion concentration and lower temperature exist. These factors are favourable for the formation of oxyhaemoglobin.
- In tissues, low pO₂, high pCO₂, high H⁺ ions and high temperature exist. So Hb₄O₈ dissociates to release O₂.
- Every 100 ml of oxygenated blood can deliver around 5 ml of O₂ to the tissues under normal physiological conditions.

Oxygen-haemoglobin dissociation curve

It is a sigmoid curve obtained when percentage saturation of Hb with O₂ is plotted against the pO₂.

It is useful to study the effect of factors like pCO₂, H⁺ concentration etc., on binding of O₂ with Hb.

2. CO₂ TRANSPORT

It is the transport of CO₂ from tissues to lungs.
In tissues, pCO₂ is high and pO₂ is low. In lungs, pCO₂ is low and pO₂ is high. This favours CO₂ transport from tissues to lungs. It occurs in 3 ways:

a. As carbonic acid: In tissues, about 7% of CO₂ is dissolved in plasma water to form carbonic acid and carried to lungs.

b. As carbamino-haemoglobin: In tissues, 20-25% of CO₂ binds to Hb to form carbamino-haemoglobin. In alveoli, CO₂ dissociates from carbamino-haemoglobin.

c. As bicarbonates: About 70% of CO₂ is transported by this method. RBCs and plasma contain an enzyme, carbonic anhydrase. This enzyme facilitates the following reactions.

In alveoli, the above reaction proceeds in opposite direction leading to the formation of CO₂ and H₂O. Every 100 ml of deoxygenated blood delivers about 4 ml of CO₂ to the alveoli.

REGULATION OF RESPIRATION

Respiratory centres present in the brain include

•  Respiratory rhythm centre (Inspiratory & Expiratory centres): In medulla oblongata.

•  Pneumotaxic centre: In Pons. It moderates the functions of the respiratory rhythm centre. Neural signal from this centre reduces the duration of inspiration and thereby alter the respiratory rate.

•  Chemosensitive area: Seen adjacent to the rhythm centre. Increase in the concentration of CO₂ and H⁺ activates this centre, which in turn signals rhythm centre. Receptors in aortic arch and carotid artery also recognize changes in CO₂ and H+ concentration and send signals to the rhythm centre. Role of oxygen in the regulation of respiratory rhythm is quite insignificant.

DISORDERS OF RESPIRATORY SYSTEM

1. Asthma: Difficulty in breathing causing wheezing due to inflammation of bronchi and bronchioles.

2. Emphysema: Damage of alveolar walls. It decreases respiratory surface. Major cause is cigarette smoking.

3. Occupational respiratory disorders: Certain industries produce so much dust. So the defense mechanism of the body cannot cope with the situation. Long exposure causes inflammation leading to fibrosis (proliferation of fibrous tissues). It results in lung damage. Workers in such industries should wear protective masks.

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