CBSE Class 12 Biotechnology Sample Paper 2025 Solved

Sample Question Papers for Class 12 Bio Technology

Explore authentic exam practice materials through the CBSE Class 12 Biotechnology Sample Paper 2025 Solved. Tailored for Class 12 learners, utilizing these Bio Technology sample papers ensures thorough preparation and strengthens time management skills before final CBSE evaluations.

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View or download the dedicated CBSE Class 12 Biotechnology Sample Paper 2025 Solved resource below. Engaging with these sample papers under timed conditions ensures continuous academic progress and mastery of the 2026-27 exam format.

Section - A

Q. No. 1 to 12 are multiple choice questions. Only one of the choices is correct. Select and write the correct choice as well as the answer to these questions.

1 An approach that utilises analysis of genome present in different environment to screen presence of variety of molecules.
A. Metagenomics
B. Proteomics
C. Strain preservation
D. Mutant selection

Answer : B

2 In animal cell culture, the CO2 levels in the incubator is usually maintained at-
A. 1-2%
B. 3-4%
C. 5-10%
D. 11-15%

Answer : C

3 Even if we know where the genes are in each genome, it’s difficult to count them due to:
(i) splice variants
(ii) overlapping genes
(iii) Post – trancriptional events
(iv) Mutations

A. (i), (iii)
B. (i), (ii)
C. (iii), (iv)
D. (ii), (iv)

Answer : B

4 Avocado growers in Kerela want to find a way to genetically engineer their crop to prevent it from ripening during shipping. This can be achieved by introducing-
A. genes for carotenoid biosynthesis.
B. gene from Bacillus amyloliquefaciens.
C. ethylene forming gene(s).
D. gene for protein containing sulphur rich amino acids.

Answer : C

5 Microbial species used for commercial production of citric acid is-
A. Saccharomyces cerevisiae
B. Aspergillus niger
C. Streptomyces griseus
D. Aspergillus oryzae

Answer : B

6 To reduce the possibility of religation of vector without picking insert, the following method or methods may be used-
(i) Use of DNA Ligase
(ii) Use of Alkaline Phosphatase
(iii) Use of two different Restriction enzymes for cloning
(iv) Hybridoma technology
Select the correct answer from options below

A. (i), (iv)
B. (ii), (iii)
C. (iii), (iv)
D. (ii), (iv)

Answer : D

7 In a comparative cDNA microarray, the cDNA obtained from the normal and diseased cells are labelled with red and green fluorescent dyes respectively. The yellow colour of the spot indicates-
A. Gene is expressed only in normal cells.
B. Gene is not expressed either in normal cells or in diseased cells.
C. Gene expressed only in diseased cells.
D. Gene expressed in equal measure in both types of cells.

Answer : D

8 Which disease has its locus on chromosome no 1 and 6?
A. Huntington's disease
B. Migraine
C. Alzheimer’s disease
D. Cystic fibrosis

Answer : B

9 A molecular disease which leads to increased hydrophobic interactions within the haemoglobin protein is-
A. Thalassemia
B. Sickle Cell anaemia
C. Mad Cow
D. SCID

Answer : B

10 Interleukin-2 produced using CHO cell line is used for-
A. anaemia therapy.
B. cancer therapy.
C. stroke.
D. treatment of autoimmune disease.  

Answer : B

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Download CBSE Sample Papers: Class 12 Bio Technology

Class 12 Bio Technology CBSE Class 12 Biotechnology Sample Paper 2025 Solved PDF Download Guide

Review model practice papers for Class 12 Bio Technology. Working through the CBSE Class 12 Biotechnology Sample Paper 2025 Solved under simulated test conditions at home ensures complete familiarity with upcoming school evaluations.

Maximize Your Scores with Model Papers

  • Original Practice Material: Access unique questions for Bio Technology designed to challenge your understanding.
  • Self-Assessment: Evaluate scores per set to pinpoint weak zones in Class 12 Bio Technology.
  • Exam Completion Skills: Routine problem sets train you to manage test duration efficiently without stress.

How to Analyze Your Performance in CBSE Class 12 Biotechnology Sample Paper 2025 Solved

  1. Verify Answers: Compare your responses against professional teacher solutions provided in the sample paper keys.
  2. Error Analysis: Class 12 learners must review incorrect answers carefully to understand underlying mistakes.
  3. Concept Reinforcement: Consult the official NCERT book for Class 12 Bio Technology when stuck before re-attempting problems.

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Yes, CBSE Class 12 Biotechnology Sample Paper 2025 Solved comes with detailed, teacher-verified solutions. We have provided step-by-step answers for Bio Technology to help students of Class 12 understand correct methodology and marking scheme.

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Practicing this Bio Technology paper helps in time management and identifying important topics. For Class 12, solving mock papers is the best way to gain confidence and reduce exam-day anxiety.

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