CBSE Class 12 Biology Human Reproduction Worksheet Set F

Access the latest CBSE Class 12 Biology Human Reproduction Worksheet Set F. We have provided free printable Class 12 Biology worksheets in PDF format, specifically designed for Chapter 2 Human Reproduction. These practice sets are prepared by expert teachers following the 2025-26 syllabus and exam patterns issued by CBSE, NCERT, and KVS.

Chapter 2 Human Reproduction Biology Practice Worksheet for Class 12

Students should use these Class 12 Biology chapter-wise worksheets for daily practice to improve their conceptual understanding. This detailed test papers include important questions and solutions for Chapter 2 Human Reproduction, to help you prepare for school tests and final examination. Regular practice of these Class 12 Biology questions will help improve your problem-solving speed and exam accuracy for the 2026 session.

Download Class 12 Biology Chapter 2 Human Reproduction Worksheet PDF

 

Very Short Answer Questions

Question. List the changes that the primary ooctye undergoes in the tertiary follicular stage in the human ovary.
Answer. The primary oocyte within the tertiary follicle grows in size and completes its first meiotic division to form secondary oocyte and first polar body.

Question. Female reproductive organs and associated functions are given below in column A and B. Fill in the blank boxes. 

CBSE Class 12 Biology Human Reproduction Worksheet Set F

Answer. A—Fertilisation

Question. Name the embryonic stage that gets implanted in the uterine wall of a human female.
Answer. Blastocyst/blastula.

Question. Males in whom testes fail to descend to the scrotum are generally infertile. Why?
Answer. If the testes fail to descend to the scrotum, gametogenesis could be inhibited. The process of spermatogenesis requires a marginally lesser (2°C less) ambient temperature than that in the abdominal cavity.

Question. What is menstrual cycle? Which hormones regulate menstrual cycle?
Answer. The reproductive cycle in the female primates is called menstrual cycle. The uterus lining becomes thick and spongy to receive fertilised egg. If the egg is not fertilised this lining is not needed any longer so, it slowly breaks and comes out through vagina as along with blood and mucous and is called menstruation.
Menstrual cycle is regulated by FSH (Follicle stimulating hormone), LH (Lutenising hormone),estrogen and progesterone.

Question. What is oogenesis? Give a brief account of oogenesis.
Answer. Oogenesis
 The process of formation of a mature female gamete is called oogenesis. It occurs in the ovaries.
It consists of the following three phases:
(a) Multiplication phase: Oogenesis is initiated during the embryonic development stage when
a couple of million gamete mother cells (oogonia) are formed within each foetal ovary. No more oogonia are formed and added after birth. These cells start division and enter into prophase-I of the meiotic division. They get temporarily arrested at this stage and are called primary oocytes.

Question. Describe the structure of a seminiferous tubule.
Answer. A seminiferous tubule is made up of layer of male germ cells and large Sertoli cells (nurse cells). The male germ cells undergo spermatogenesis to produce spermatocytes, spermatids and sperms. The regions outside the seminiferous tubules called interstitial spaces have connective tissue which includes blood vessels and Leydig cells (interstitial cells). Leydig cells synthesise and secrete the male sex hormones called androgens, of which testosterone is the principle one.
For diagram,

CBSE Class 12 Biology Human Reproduction Worksheet Set F
Diagrammatic sectional view of a seminiferous tubule (enlarged)

Question. How is the entry of only one sperm and not many ensured into an ovum during fertilisation in humans? 
Answer. During fertilisation a sperm head comes in contact with zona pellucida layer of ovum and induces changes in the membrane that block the entry of additional sperms.

Short Answer Questions

Question. Explain the events that follow up to fertilisation when the sperms come in contact with the ovum in the fallopian tube of a human female.
Answer. The secretion of the acrosome help the sperm enter into the cytoplasm of ovum through zona pellucida and the plasma membrane. This induce the completion of second meiotic division of the secondary oocyte, forming second polar body and a haploid ovum. Soon the haploid nucleus of the sperm and that of the ovum fuse together to form a diploid zygote.

Question. When and where do chorionic villi appear in humans? State their functions. 
Answer. Chorionic villi appear after implantation on the trophoblast. It becomes interdigitated with uterine tissue to form the placenta and increases the surface area for exchange of materials between the mother and the embryo.

Question. Name two hormones that can be found only in the blood of a pregnant woman. Mention the source organ/tissue that secretes each of them. 
Answer. Human chorionic gonadotropin (hCG)—Placenta.
Human placental lactogen (hPL)—Placenta.
Relaxin (towards the end of pregnancy)—Ovary.

Question. Mention the target cells of luteinising hormone in human males and females. Explain the effect and the changes which the hormone induces in each case.
Answer. The target cells of luteinising hormone (LH) in males are the Leydig cells and in females are the mature growing follicles.
LH in males stimulates the Leydig cells (interstitial cells) of testes to synthesise and secrete androgens which in turn stimulate the process of spermatogenesis. LH in females stimulate the ovulation (release of ovum) and transformation of Graafian follicle into corpus luteum to secrete progesterone which prepares the endometrium to receive and implant blastocyst.

Question. State the role of oxytocin in parturition. What triggers its release from the pituitary?
Answer. Oxytocin acts on uterine muscle and cause stronger uterine contraction. This leads to expulsion of the foetus or baby out of uterus.

Question. Write the effect of the high concentration of LH on a mature Graafian follicle. 
Answer. In high conventration of LH, the mature Graafian follicle ruptures to release the secondary oocyte or ovum from the ovary by the process of ovulation.

Question. After implantation interdigitation of maternal and foetal tissues takes place. Identify the tissues involved and justify their role.
Answer. After implantation interdigitation of maternal and foetal tissues results in formation of structural and functional unit between embryo and maternal body called placenta.
It facilitates supply of oxygen and nutrients to the embryo, removal of carbon dioxide and excretory material and also acts as an endocrine tissue and produces hormones like HCG, hPL, estrogen, progesterone and relaxin.

Question. Draw a labelled diagram of a human blastocyst. How does it get implanted in the uterus?
Answer. Human blastocyst

CBSE Class 12 Biology Human Reproduction Worksheet Set F

The trophoblast layer of the blastocyst gets attached to the cells of the endometrium and the inner cell mass gives rise to the embryo. The cells of endometrium divide rapidly and cover the blastocyst. So, the blastocyst gets embedded in the endometrium of the uterus.

HUMAN REPRODUCTION
 
Q.1. In a mammalian sperm , spirally arranged mitochondria around the axial filament are present in the region of the : *
(1) Head
(2) Middle piece
(3) Principal piece of the tail
(4) End piece of tail
 
Q.2. Which of the following hormones is not a secretion product of human placenta : *
(1) human chorionic gonadotropin
(2) prolactin
(3) estrogen
(4) progesterone
 
Q.3. FSH is secreted by: *
(1) Adrenal
(2) Thyroid
(3) Anterior pituitary
(4) Posterior pituitary
 
Q.4. Sperms of mammals depend for movement on: *
(1) tail
(2) middle piece
(3) head
(4) tail and middle piece
 
Q.5. Phase of menstrual cycle that lasts for 7-8 days: *
(1) Menstruation
(2) Luteal phase
(3) Ovulatory phase
(4) Follicular phase
 
Q.6.Embryo at 16-celled stage is called : *
(1) Morula
(2) Blastomere
(3) Blastula
(4) Gastrula
 
Q.7. Egg is liberated from ovary in : *
(1) secondary oocyte stage
(2) primary oocyte stage
(3) oogonial stage
(4) mature ovum stage
 
Q.8.Ovulation occurs under the influence of: *
(1) LH
(2) FSH
(3) Estrogen
(4) Progesterone
 
Q.9. The mammary glands of female starts producing milk: *
(1)At the end of menopause
(2) At the time of puberty
(3) At the end of pregnancy
(4) Start of pregnancy
 
Q.10. At the end of first meiotic division, male germ differentiates into : *
(1) secondary spermatocte
(2) primary spermatocyte
(3) spermatogonium
(4) spermatid
 
Q.11. Progesterone is called pregnancy hormone as it helps in *
(1) lactation
(2) maintaining pregnancy and bring about labour pain
(3) help in causing contraction of uterus for delivery
(4) release of ovum from ovary
 
Q.12. Withdrawal of which of the following hormones is the immediate cause of menstruation? *
(1) Estrogen
(2) FSH
(3) FSH-RH
(4) Progesterone
 
Q.13. Assertion : The first milk after the birth of baby is called colostrum , it is good to give this milk to infant . Reason: Colostrum is rich in proteins , calories and antibodies . *
(1) Assertion and reason both are correct .
(2) Assertion is correct but reason is incorrect.
(3) Assertion is incorrect but reason is correct.
(4) Both assertion and reason are incorrect.
 
Q.14. Seminal plasma in humans is rich in: *
(1) glucose and certain enzymes but has no calcium
(2) fructose and calcium but has no enzymes
(3) glucose , calcium and certain enzymes
(4) fructose, calcium and certain enzymes
 
Q.15. How many autosomes does a human primary spermatocyte have *
(1) 22
(2) 44
(3) 54
(4) 33

 

Please click on below link to download CBSE Class 12 Biology Human Reproduction Worksheet Set F

Chapter 2 Human Reproduction CBSE Class 12 Biology Worksheet

Students can use the Chapter 2 Human Reproduction practice sheet provided above to prepare for their upcoming school tests. This solved questions and answers follow the latest CBSE syllabus for Class 12 Biology. You can easily download the PDF format and solve these questions every day to improve your marks. Our expert teachers have made these from the most important topics that are always asked in your exams to help you get more marks in exams.

NCERT Based Questions and Solutions for Chapter 2 Human Reproduction

Our expert team has used the official NCERT book for Class 12 Biology to create this practice material for students. After solving the questions our teachers have also suggested to study the NCERT solutions  which will help you to understand the best way to solve problems in Biology. You can get all this study material for free on studiestoday.com.

Extra Practice for Biology

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