NEET Biology Principles of Inheritance and Variation MCQs Set 19

Multiple Choice Questions (MCQs) for NEET Biology: Principles of Inheritance and Variation

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Multiple Choice Questions

Question 1: Which of the following crosses will produce a 1 : 1 phenotypic ratio?
(a) AaBb × aabb
(b) AaBB × aaBB
(c) aabb × aabb
(d) AABB × aabb
Show Answer & Explanation

Answer: (b) AaBB × aaBB

Explanation:
1. AaBB × aaBB gives AaBB and aaBB in equal numbers, so the phenotypes are 1 : 1.
2. AaBb × aabb gives 1 : 1 : 1 : 1.

Teacher's Note:
1. The other two crosses give a single phenotype.

Question 2: In corn, tall (T) is dominant to dwarf (t) and coloured kernel (C) is dominant to white (c). In a particular cross the probability of a tall offspring is 0.5 and of a coloured kernel is 0.75. The most probable parental genotypes are:
(a) TtCc × TtCc
(b) TtCc × ttCc
(c) TtCc × ttcc
(d) TTCc × ttCc
Show Answer & Explanation

Answer: (b) TtCc × ttCc

Explanation:
1. A tall probability of 1/2 needs Tt × tt.
2. A coloured probability of 3/4 needs Cc × Cc.
3. Combining them gives TtCc × ttCc.

Teacher's Note:
1. Break a two-gene problem into two single-gene problems.

Question 3: A hybrid with 81 genotypes on selfing will produce how many phenotypes (complete dominance)?
(a) 81
(b) 16
(c) 8
(d) 32
Show Answer & Explanation

Answer: (b) 16

Explanation:
1. \( 81 = 3^4 \) genotypes means four heterozygous gene pairs.
2. The number of phenotypes is \( 2^4 = 16 \).

Teacher's Note:
1. Genotypes follow \( 3^n \) and phenotypes follow \( 2^n \).

Question 4: What is the probability of obtaining pure homozygous individuals (for all four genes) in the cross AaBbCcDd × aaBBCCdd?
(a) 2/16
(b) 1/16
(c) 1/32
(d) 1/64
Show Answer & Explanation

Answer: (b) 1/16

Explanation:
1. Each gene gives a homozygous offspring with probability 1/2 (Aa × aa, Bb × BB, Cc × CC, Dd × dd).
2. So the probability is \( (1/2)^4 = 1/16 \).

Teacher's Note:
1. Multiply the probabilities for the four genes.

Question 5: A human male is heterozygous for two autosomal genes A and B and homozygous dominant for a third autosomal gene C. He has the sry gene (S) on his Y chromosome. What is the probability of his sperms carrying the abcS condition?
(a) 1/4
(b) 1/8
(c) 0
(d) 1/16
Show Answer & Explanation

Answer: (c) 0

Explanation:
1. The male is CC, so he cannot form a sperm with allele \( c \).
2. The abcS combination is therefore impossible, and the probability is zero.

Teacher's Note:
1. Check for homozygous genes first, since they can make a combination impossible.

Question 6: From hybridisation experiments on the garden pea, Mendel proposed that something was stably passed from parent to offspring through gametes. He called these things:
(a) Genes
(b) Factors
(c) Alleles
(d) Multiple genes
Show Answer & Explanation

Answer: (b) Factors

Explanation:
1. Mendel called the units of inheritance factors.
2. The word gene was introduced later by Johannsen.

Teacher's Note:
1. Factors are what we now call genes.

Question 7: A child has blood group O. The father has blood group A and the mother has blood group B. Which statement is incorrect?
(a) The child is homozygous for blood group O
(b) The father is homozygous for blood group A
(c) The mother is heterozygous for blood group B
(d) Both (a) and (b)
Show Answer & Explanation

Answer: (b) The father is homozygous for blood group A

Explanation:
1. The \( O \) child is ii, so each parent must carry \( i \).
2. The father is therefore IAi (heterozygous), and the mother is IBi.

Teacher's Note:
1. Hence statement \( (b) \) is incorrect, while \( (a) \) and \( (c) \) are correct.

Question 8: When a pure green-pod pea plant is crossed with a yellow-pod plant (green dominant), yellow-pod plants in the F2 generation will be:
(a) 75%
(b) 50%
(c) 25%
(d) 37.5%
Show Answer & Explanation

Answer: (c) 25%

Explanation:
1. Green is dominant, so \( F1 \) is all heterozygous green.
2. In \( F2 \) the ratio is 3 green : 1 yellow, so yellow plants are 25%.

Teacher's Note:
1. The recessive trait reappears in one quarter of the \( F2 \).

Question 9: What is correct about a true-breeding pea line?
(a) A true-breeding line, after continuous self-pollination, shows stable trait inheritance for several generations
(b) Mendel selected 14 true-breeding pea varieties, as pairs similar except for one contrasting character
(c) Mendel selected 7 true-breeding pea varieties, as pairs similar except for one contrasting character
(d) Both (a) and (b)
Show Answer & Explanation

Answer: (d) Both (a) and (b)

Explanation:
1. A true-breeding line shows stable inheritance after continuous selfing.
2. Mendel used 14 true-breeding varieties arranged as 7 pairs of contrasting traits.

Teacher's Note:
1. So statements \( (a) \) and \( (b) \) are correct and \( (c) \) is wrong.

Question 10: Which law explains the 3 : 1 proportion obtained in the F2 of a monohybrid cross?
(a) Law of dominance
(b) Theory of linkage
(c) Law of independent assortment
(d) Both (b) and (c)
Show Answer & Explanation

Answer: (a) Law of dominance

Explanation:
1. In the monohybrid \( F2 \) the dominant and recessive traits appear in a 3 : 1 ratio because one allele dominates the other.
2. The law of segregation explains why the recessive trait reappears.

Teacher's Note:
1. Independent assortment applies to two or more genes.

Question 11: In which case is dominance NOT an autonomous feature of a gene or of the product it carries information for?
(a) Multiple allele
(b) Multiple gene
(c) Polygenic inheritance
(d) More than one phenotype influenced by the same gene
Show Answer & Explanation

Answer: (d) More than one phenotype influenced by the same gene

Explanation:
1. When one gene influences more than one phenotype (pleiotropy), dominance depends on the phenotype under consideration.
2. The same allele can be dominant for one effect and recessive for another.

Teacher's Note:
1. Dominance is thus not an independent property of the gene.

Question 12: Who argued that the pairing and separation of a pair of chromosomes would lead to the segregation of a pair of factors they carried?
(a) Thomas Hunt Morgan and Alfred Sturtevant
(b) Mendel and Bateson
(c) Sutton and Boveri
(d) Carl Correns and Hugo de Vries
Show Answer & Explanation

Answer: (c) Sutton and Boveri

Explanation:
1. Sutton and Boveri proposed the chromosomal theory of inheritance.
2. They noted that chromosome behaviour parallels the behaviour of Mendel's factors.

Teacher's Note:
1. Morgan later gave experimental proof using Drosophila.

Question 13: Which of the following provides a good example of multiple alleles?
(a) ABO blood group
(b) Sickle-cell anaemia
(c) Flower colour in dog flower plant
(d) Starch synthesis in garden pea seeds
Show Answer & Explanation

Answer: (a) ABO blood group

Explanation:
1. The ABO blood group is controlled by three alleles (IA, IB and \( i \)) of one gene.
2. Sickle-cell anaemia has two alleles.

Teacher's Note:
1. Remember that an individual carries only two alleles, so multiple alleles are seen only in a population.

Question 14: Mendel crossed round yellow seeded pea plants with wrinkled green seeded plants. In the F2 generation the probability of plants having wrinkled seeds is:
(a) 3/16
(b) 1/16
(c) 12/16
(d) 4/16
Show Answer & Explanation

Answer: (d) 4/16

Explanation:
1. Wrinkled seeds (rr) form 1/4 of the \( F2 \), which is 4/16.
2. The wrinkled plants include yellow wrinkled (3/16) and green wrinkled (1/16).

Teacher's Note:
1. Add them: \( 3/16 + 1/16 = 4/16 \).

Question 15: Which statement can be explained on the basis of the law of dominance?
(a) Characters are controlled by discrete units called factors
(b) Factors occur in pairs
(c) In a dissimilar pair of factors one member of the pair dominates the other
(d) All of the above
Show Answer & Explanation

Answer: (d) All of the above

Explanation:
1. The law of dominance has three parts: characters are controlled by discrete factors, factors occur in pairs, and in a dissimilar pair one factor dominates.
2. All three statements belong to it.

Teacher's Note:
1. So the answer is all of the above.

Question 16: Which genetic disorder is caused by aneuploidy of autosomes?
(a) Klinefelter's syndrome
(b) Turner's syndrome
(c) Down's syndrome
(d) Phenylketonuria
Show Answer & Explanation

Answer: (c) Down's syndrome

Explanation:
1. Down's syndrome is trisomy of chromosome 21, an autosome.
2. Klinefelter's (XXY) and Turner's (XO) involve sex chromosomes, and phenylketonuria is a gene (enzyme) defect.

Teacher's Note:
1. Aneuploidy means a gain or loss of single chromosomes.

Question 17: Genes or alleles that can express independently when present together and also follow the law of segregation are:
(a) Multiple genes
(b) Codominant genes
(c) Epistatic genes
(d) Complementary genes
Show Answer & Explanation

Answer: (b) Codominant genes

Explanation:
1. In codominance both alleles of a pair express themselves in the heterozygote, for example IA and IB.
2. They still segregate during gamete formation.

Teacher's Note:
1. Codominance is therefore consistent with the law of segregation.

Question 18: The maximum height of a plant is 30 ft and the minimum is 10 ft. If height is controlled by 3 pairs of genes (polygenic, additive), the height of a plant of genotype AaBbCc will be about:
(a) 13.2 ft
(b) 23.2 ft
(c) 16.6 ft
(d) 19.9 ft
Show Answer & Explanation

Answer: (d) 19.9 ft

Explanation:
1. There are 6 alleles shared over a 20 ft range, so each contributing allele adds about 3.3 ft.
2. AaBbCc has three contributing alleles, giving \( 10 + 3 \times 3.3 = 19.9 \) ft.

Teacher's Note:
1. It is the mid-value, as expected for a heterozygote.

Question 19: What percentage of F2 progeny will have broad leaves and pink flowers in Snapdragon, if leaf shape shows dominance and flower colour shows incomplete dominance?
(a) 37.5%
(b) 56.25%
(c) 62.5%
(d) 12.5%
Show Answer & Explanation

Answer: (a) 37.5%

Explanation:
1. Broad leaves (dominant) occur in 3/4 of the \( F2 \).
2. Pink flowers (heterozygotes) occur in 1/2 of the \( F2 \).

Teacher's Note:
1. The combined probability is \( 3/4 \times 1/2 = 3/8 \) = 37.5%.

Question 20: A white-fruited summer squash plant of genotype WwYy is crossed with a plant of genotype wwyy (white W_ is epistatic over Y and y). Then:
(a) 25% of the offspring will have yellow fruits
(b) All the progeny have white fruits
(c) 75% of the plants have white fruits
(d) 6.25% of the plants have green fruits
Show Answer & Explanation

Answer: (a) 25% of the offspring will have yellow fruits

Explanation:
1. The offspring are WwYy and Wwyy (white, 50%), wwYy (yellow, 25%) and wwyy (green, 25%).
2. So 25% have yellow fruits.

Teacher's Note:
1. This is dominant epistasis, where \( W \) masks the effect of \( Y \).

Question 21: What percentage of pea seeds will have intermediate-sized starch grains in the F2 generation (BB large, Bb intermediate, bb small)?
(a) 0%
(b) 25%
(c) 50%
(d) 75%
Show Answer & Explanation

Answer: (c) 50%

Explanation:
1. The \( F2 \) genotypic ratio is 1 BB : 2 Bb : 1 bb.
2. Heterozygotes (Bb) have intermediate starch grains, so they are 50%.

Teacher's Note:
1. Here the heterozygote shows an intermediate phenotype.

Question 22: Select the wrong statement with respect to multiple alleles.
(a) It can be detected only in a population
(b) They are mutant forms of the same gene
(c) The number of phenotypes in multiple alleles is calculated by the formula 2n + 1
(d) They occupy the same locus on homologous chromosomes
Show Answer & Explanation

Answer: (c) The number of phenotypes in multiple alleles is calculated by the formula 2n + 1

Explanation:
1. Multiple alleles are alternative forms of one gene at the same locus, seen only in a population.
2. The number of phenotypes does not follow a fixed formula like \( 2n + 1 \), because it depends on dominance relations.

Teacher's Note:
1. Hence statement \( (c) \) is wrong.

Multiple Choice Questions (MCQs) for NEET Biology Principles of Inheritance and Variation

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