NEET Biology Principles of Inheritance and Variation MCQs Set 20

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Chapter-wise Objective Questions: Principles of Inheritance and Variation

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Multiple Choice Questions

Question 1: A man and woman who both appear normal have a child with sickle-cell anaemia. The woman is pregnant with fraternal (dizygotic) twins. What is the probability that both twins will have sickle-cell anaemia?
(a) 1/16
(b) 1/4
(c) 1/2
(d) 9/16
Show Answer & Explanation

Answer: (a) 1/16

Explanation:
1. Both parents must be carriers (Aa).
2. Each child has a 1/4 chance of being affected, and fraternal twins are independent events.

Teacher's Note:
1. So the probability for both is \( 1/4 \times 1/4 = 1/16 \).

Question 2: In co-dominance the genes of an allelomorphic pair express ______ and follow the law of ______.
(a) Equally, independent assortment
(b) Unequally, dominance
(c) Equally, segregation
(d) Equally, dominance
Show Answer & Explanation

Answer: (c) Equally, segregation

Explanation:
1. In codominance both alleles are expressed equally in the heterozygote.
2. The alleles still separate in gametes, following the law of segregation.

Teacher's Note:
1. They do not follow dominance because neither masks the other.

Question 3: In Mirabilis jalapa, what percentage of plants will have pink and red flowers when a pink-flowered plant is test crossed?
(a) 25% pink and 25% red
(b) 50% pink and 50% red
(c) 50% pink and 0% red
(d) 0% pink and 50% red
Show Answer & Explanation

Answer: (c) 50% pink and 0% red

Explanation:
1. Pink is the heterozygote (Rr), and the test cross is with the recessive white (rr).
2. The offspring are 1/2 Rr (pink) and 1/2 rr (white), so there are no red plants.

Teacher's Note:
1. Red would need a homozygous RR parent.

Question 4: Multiple alleles can be found only when a population is studied because:
(a) An individual has only two alleles
(b) A single trait is controlled by more than two alleles
(c) A single gene affects different characters
(d) It has quantitative inheritance
Show Answer & Explanation

Answer: (a) An individual has only two alleles

Explanation:
1. A diploid individual carries only two alleles of a gene.
2. More than two alleles can be seen only by comparing many individuals of a population.

Teacher's Note:
1. Hence multiple alleles are a population-level feature.

Question 5: What is the phenotypic ratio on selfing a trihybrid in which two genes show complete dominance and one shows incomplete dominance?
(a) 3 : 6 : 3 : 1 : 2 : 1
(b) 27 : 9 : 9 : 9 : 3 : 1 : 3 : 3
(c) 18 : 6 : 6 : 2 : 9 : 3 : 3 : 1 : 9 : 3 : 3 : 1
(d) 18 : 6 : 6 : 2 : 9 : 3 : 3 : 1 : 1 : 2 : 1
Show Answer & Explanation

Answer: (c) 18 : 6 : 6 : 2 : 9 : 3 : 3 : 1 : 9 : 3 : 3 : 1

Explanation:
1. Multiply (3 : 1) × (3 : 1) × (1 : 2 : 1).
2. This gives 12 phenotype classes: 9, 18, 9, 3, 6, 3, 3, 6, 3, 1, 2, 1 parts.

Teacher's Note:
1. Option \( (c) \) lists exactly these twelve values.

Question 6: If the four children of a family have four different blood groups (A, B, AB and O), the genotypes of the father and mother are:
(a) IAIA and IBIB
(b) IAIO and IBIB
(c) IAIO and IBIO
(d) IAIA and IBIO
Show Answer & Explanation

Answer: (c) IAIO and IBIO

Explanation:
1. All four groups appear only when each parent carries the \( O \) allele and one different dominant allele.
2. IAIO × IBIO gives IAIB, IAIO, IBIO and IOIO.

Teacher's Note:
1. No other combination can produce all four groups.

Question 7: The ratio of carrier : disease-free : diseased individuals in the marriage of two carriers of sickle-cell anaemia is:
(a) 0 : 2 : 1
(b) 0 : 1 : 1
(c) 1 : 2 : 1
(d) 2 : 1 : 1
Show Answer & Explanation

Answer: (d) 2 : 1 : 1

Explanation:
1. Aa × Aa gives 1 AA (disease free), 2 Aa (carriers) and 1 aa (diseased).
2. So the ratio of carrier : free : diseased is 2 : 1 : 1.

Teacher's Note:
1. Read the order asked in the question carefully.

Question 8: A monohybrid cross between a plant with 24 cm long internodes and a plant with 12 cm long internodes produces F1 hybrids all with 18 cm internodes. This is a case of:
(a) Complete dominance
(b) Incomplete dominance
(c) Co-dominance
(d) Multiple allelism
Show Answer & Explanation

Answer: (b) Incomplete dominance

Explanation:
1. The \( F1 \) shows a phenotype intermediate between the two parents.
2. This is the pattern of incomplete dominance.

Teacher's Note:
1. In complete dominance the \( F1 \) would resemble one parent.

Question 9: In polygenic inheritance of skin colour controlled by two polygenes, the number of phenotypes, the number of mulattoes (intermediate types) and the total progeny in F2 are:
(a) 3, 3, 16
(b) 5, 6, 16
(c) 7, 20, 64
(d) 7, 6, 16
Show Answer & Explanation

Answer: (b) 5, 6, 16

Explanation:
1. With two gene pairs \( F2 \) shows 5 phenotype classes (4, 3, 2, 1 or 0 contributing alleles) in the ratio 1 : 4 : 6 : 4 : 1 out of 16.
2. The mulatto classes with 2 dominant alleles number 6.

Teacher's Note:
1. Total \( F2 \) combinations are 16.

Question 10: What phenotypic ratio is expected in the F2 of a dihybrid cross if both genes cause lethality in the homozygous dominant state?
(a) 2 : 2 : 2 : 2
(b) 4 : 2 : 2 : 1
(c) 6 : 3 : 2 : 1
(d) 9 : 3 : 3 : 1
Show Answer & Explanation

Answer: (b) 4 : 2 : 2 : 1

Explanation:
1. The AA and BB zygotes die.
2. The survivors are 2 Aa : 1 aa for the first gene and 2 Bb : 1 bb for the second.

Teacher's Note:
1. Multiplying gives 4 : 2 : 2 : 1.

Question 11: How many genotypes are produced in the F2 of a dihybrid cross if both genes are pleiotropic?
(a) 3
(b) 4
(c) 9
(d) Cannot be calculated
Show Answer & Explanation

Answer: (c) 9

Explanation:
1. Pleiotropy does not change the genetic ratio.
2. Two heterozygous gene pairs give \( 3 \times 3 = 9 \) genotypes in \( F2 \).

Teacher's Note:
1. Pleiotropy affects phenotypes, not genotype counts.

Question 12: If a trait is controlled by 2 polygenes, the total number of phenotypes and genotypes together in F2 is:
(a) 13
(b) 8
(c) 14
(d) 27
Show Answer & Explanation

Answer: (c) 14

Explanation:
1. Two polygenes give 5 phenotype classes and \( 3 \times 3 = 9 \) genotypes in \( F2 \).
2. Their total is \( 5 + 9 = 14 \).

Teacher's Note:
1. Compare with the \( 2^n \) and \( 3^n \) rules of ordinary dihybrid crosses.

Question 13: In the pea plant, when a homozygous round-seeded plant is crossed with a homozygous wrinkled-seeded plant, the offspring will be (starch grain size shows incomplete dominance):
(a) 100% with large starch grains
(b) 75% with medium-sized starch grains
(c) 25% with small starch grains
(d) 0% with small starch grains
Show Answer & Explanation

Answer: (d) 0% with small starch grains

Explanation:
1. All \( F1 \) plants are heterozygous (Bb) and have intermediate-sized starch grains.
2. So none have small grains.

Teacher's Note:
1. The cross gives a uniform \( F1 \), as in the law of dominance.

Question 14: Genes C and P are complementary in sweet pea and produce coloured flowers when present together. The product of the cross CcPp × Ccpp is:
(a) 2 white and 6 coloured
(b) 3 white and 5 coloured
(c) 2 coloured and 6 white
(d) 3 coloured and 5 white
Show Answer & Explanation

Answer: (d) 3 coloured and 5 white

Explanation:
1. Coloured flowers need \( C_ \) and \( P_ \).
2. In CcPp × Ccpp, \( C_ \) has probability 3/4 and Pp × pp gives \( P_ \) with probability 1/2, so coloured = 3/8.

Teacher's Note:
1. Out of 8, 3 are coloured and 5 are white.

Question 15: Height of a plant shows polygenic inheritance. Plant A1A1A0A0 is 56 cm tall and plant a1a1a0a0 is 26 cm tall. The contribution of each (capital) allele is:
(a) 30 cm
(b) 8.5 cm
(c) 15 cm
(d) 7.5 cm
Show Answer & Explanation

Answer: (d) 7.5 cm

Explanation:
1. The difference of 30 cm is due to four capital alleles.
2. Each allele therefore adds \( 30 / 4 = 7.5 \) cm.

Teacher's Note:
1. This is additive gene action.

Question 16: In the same cross, the height of a plant of genotype A1A1A0a0 will be:
(a) 26 cm
(b) 48.5 cm
(c) 56 cm
(d) 22.5 cm
Show Answer & Explanation

Answer: (b) 48.5 cm

Explanation:
1. The plant has three capital alleles, each adding 7.5 cm to the base height of 26 cm.
2. Height = \( 26 + 3 \times 7.5 = 48.5 \) cm.

Teacher's Note:
1. Count contributing alleles and multiply.

Question 17: A red-eyed female Drosophila is crossed with a white-eyed male. If 50% of the progeny are red eyed, we can say that:
(a) Both parents were hemizygous
(b) The female parent was heterozygous
(c) The female parent was pure
(d) Both parents were pure
Show Answer & Explanation

Answer: (b) The female parent was heterozygous

Explanation:
1. XWXw × XwY gives red and white eyes in equal numbers.
2. A pure red female (XWXW) would give all red progeny.

Teacher's Note:
1. So the female must be heterozygous.

Question 18: In a linear chromosome the map distances between four loci are ab = 12, bc = 4, ad = 2 and ac = 8. The distance between c and d will be:
(a) 10%
(b) 6%
(c) 10% or 6%
(d) 3% or 6%
Show Answer & Explanation

Answer: (c) 10% or 6%

Explanation:
1. The order \( b-c-a \) is fixed by the first three distances.
2. Locus \( d \) is 2 units from a, so it can be between \( c \) and a (cd = \( 8 - 2 = 6 \)) or beyond a (cd = \( 8 + 2 = 10 \)).

Teacher's Note:
1. Both are possible with the data given.

Question 19: In Drosophila the X/A ratio determines sexual morphology. Find the incorrect match.
(a) 3X/2A - super female
(b) 2X/3A - female
(c) X/2A - male
(d) X/3A - super male
Show Answer & Explanation

Answer: (b) 2X/3A - female

Explanation:
1. A ratio of \( 2X/3A \) is 0.67, which gives an intersex, not a normal female.
2. The other matches are correct: 1.5 is metafemale, 0.5 is male and 0.33 is supermale.

Teacher's Note:
1. Normal females have a ratio of 1.0.

Question 20: In a certain taxon of insects some have 17 chromosomes and the others have 18. The organisms with 17 and 18 chromosomes are:
(a) Males and females respectively
(b) Females and males respectively
(c) All males
(d) All females
Show Answer & Explanation

Answer: (a) Males and females respectively

Explanation:
1. This is XO type sex determination.
2. Males are XO (17) and females are XX (18).

Teacher's Note:
1. The male is therefore heterogametic, producing gametes with and without the \( X \).

Question 21: What is the percentage inheritance of an X-linked disorder from a diseased father to his son?
(a) 0%
(b) 25%
(c) 50%
(d) 100%
Show Answer & Explanation

Answer: (a) 0%

Explanation:
1. A son receives the \( Y \) chromosome from his father and the \( X \) from his mother.
2. An X-linked gene of the father therefore cannot pass to a son.

Teacher's Note:
1. The father passes it to all his daughters.

Question 22: A lady whose father was colourblind and whose mother was normal marries a man suffering from hypertrichosis and haemophilia. What percentage of their offspring carry alleles for two of these traits in their genotype?
(a) 0%
(b) 25%
(c) 50%
(d) 75%
Show Answer & Explanation

Answer: (c) 50%

Explanation:
1. The lady is XCXc and the man is XhY(hypertrichosis).
2. Sons XcY(hyper) carry colourblindness plus hypertrichosis (25% of all offspring), and daughters XcXh carry two X-linked alleles (25%).

Teacher's Note:
1. Total = 50%.

Principles of Inheritance and Variation Objective Questions & Solutions for NEET Biology

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