NEET Biology Principles of Inheritance and Variation MCQs Set 18

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Multiple Choice Questions

Question 1: The total number of phenotypes and genotypes together in the F2 generation of a trihybrid cross is:
(a) 35
(b) 27
(c) 8
(d) 64
Show Answer & Explanation

Answer: (a) 35

Explanation:
1. A trihybrid \( F2 \) has \( 2^3 = 8 \) phenotypes and \( 3^3 = 27 \) genotypes.
2. Their total is \( 8 + 27 = 35 \).

Teacher's Note:
1. Remember: \( n \) gene pairs give \( 2^n \) phenotypes and \( 3^n \) genotypes in \( F2 \).

Question 2: Genes a, b and c assort independently and are recessive to their respective alleles A, B and C. Two triple heterozygous (AaBbCc) individuals are crossed. The probability that an offspring is homozygous dominant for all three genes is:
(a) 2/64
(b) 27/64
(c) 1/64
(d) 6/64
Show Answer & Explanation

Answer: (c) 1/64

Explanation:
1. The probability of AA from Aa × Aa is 1/4, and the same for BB and CC.
2. Multiplying gives \( 1/4 \times 1/4 \times 1/4 = 1/64 \).

Teacher's Note:
1. Use the product rule for independent genes.

Question 3: Which characters of the garden pea are expressed only in the homozygous condition? (A) Constricted pod (B) Green seed colour (C) Axial flower (D) Yellow pod
(a) A, B and D
(b) A, C and D
(c) B, C and D
(d) A, B and C
Show Answer & Explanation

Answer: (a) A, B and D

Explanation:
1. Recessive traits appear only when homozygous.
2. Constricted pod, green seed colour and yellow pod are recessive, whereas axial flower is dominant.

Teacher's Note:
1. Learn the seven contrasting pairs with their dominant member.

Question 4: Mendel published his work on inheritance in 1865, but it remained unrecognised till 1900. Which of the following were reasons? (A) Communication was not easy in those days (B) His contemporaries did not accept factors as discrete units of heredity (C) The mathematical approach to explain inheritance was totally new (D) Mendel could not provide any physical proof for the existence of factors
(a) Only A and B
(b) Only B and C
(c) Only C and D
(d) All are correct
Show Answer & Explanation

Answer: (d) All are correct

Explanation:
1. NCERT lists all four reasons: poor communication, non-acceptance of discrete factors, a new mathematical approach and no physical proof of factors.
2. Hence every statement is correct.

Teacher's Note:
1. Such multi-statement questions are best solved by testing each statement separately.

Question 5: When a hybrid AaBbCcDd is selfed, the genotypes AABbCCDd, AaBBCcDd, AaBbCcDd and aabbccdd appear in the proportion:
(a) 2 : 4 : 8 : 21
(b) 4 : 8 : 16 : 1
(c) 4 : 8 : 16 : 27
(d) 8 : 4 : 16 : 81
Show Answer & Explanation

Answer: (b) 4 : 8 : 16 : 1

Explanation:
1. Their probabilities are \( 1/64, 1/32, 1/16 \) and 1/256 respectively.
2. Multiplying each by 256 gives 4 : 8 : 16 : 1.

Teacher's Note:
1. Multiply the single-gene probabilities (1/4 for homozygous, 1/2 for heterozygous) for each genotype.

Question 6: Which statement is NOT true for a test cross?
(a) The F2 dihybrid test cross ratio is 1 : 1 : 1 : 1
(b) It is performed to know the alleles of a gene in an individual
(c) A test cross is a back cross
(d) Dominant offspring in a test cross are always homozygous
Show Answer & Explanation

Answer: (d) Dominant offspring in a test cross are always homozygous

Explanation:
1. A test cross is a cross of an unknown dominant phenotype with the homozygous recessive parent.
2. Dominant offspring are heterozygous when the tested individual is heterozygous, so they are not always homozygous.

Teacher's Note:
1. A test cross is a special kind of back cross.

Question 7: What percentage of offspring have the genotype AABbCc in the F2 generation of a trihybrid cross?
(a) 12.5%
(b) 6.25%
(c) 25%
(d) 37.5%
Show Answer & Explanation

Answer: (b) 6.25%

Explanation:
1. P(AA) = 1/4, P(Bb) = 1/2, P(Cc) = 1/2, so the product is 1/16 = 6.25%.
2. Heterozygous genotypes have probability 1/2 and homozygous genotypes 1/4 for each gene in a selfed hybrid.

Teacher's Note:
1. Always convert the fraction to a percentage at the end.

Question 8: The total number of genotypes and phenotypes (added together) obtained in a dihybrid test cross is:
(a) 9
(b) 8
(c) 16
(d) 13
Show Answer & Explanation

Answer: (b) 8

Explanation:
1. A dihybrid test cross (AaBb × aabb) gives 4 genotypes and 4 phenotypes in the ratio 1 : 1 : 1 : 1.
2. Their total is 8.

Teacher's Note:
1. Note that the 9 genotypes and 4 phenotypes belong to the dihybrid \( F2 \), not to the test cross.

Question 9: In man brown eyes (B) are dominant to blue (b), and dark hair (R) is dominant to red hair (r). A brown-eyed, dark-haired man marries a blue-eyed, dark-haired woman and they have one blue-eyed, red-haired child. The probable genotypes of the man, woman and child are respectively:
(a) BBRR, bbRR, bbrr
(b) BBRr, bbRr, bbrr
(c) BbRr, bbRr, bbrr
(d) BbRR, bbRR, bbRr
Show Answer & Explanation

Answer: (c) BbRr, bbRr, bbrr

Explanation:
1. The child bbrr received \( b \) and \( r \) from each parent.
2. So the man must carry \( b \) and \( r \) (BbRr) and the woman must carry \( r \) (bbRr).

Teacher's Note:
1. Always start from the recessive child to find hidden alleles in the parents.

Question 10: The frequency of pure round-seeded pea plants (RR) in the F2 generation of a dihybrid cross is:
(a) 4/16
(b) 6/16
(c) 1/16
(d) 2/16
Show Answer & Explanation

Answer: (a) 4/16

Explanation:
1. RR occurs in 1/4 of the \( F2 \) plants, whatever the other gene is.
2. Out of 16 combinations 4 are RR, i.e.
3. 4/16.

Teacher's Note:
1. Pure round means homozygous for round, regardless of the second character.

Question 11: How many types of gametes are produced by an individual of genotype AABBCcDdee?
(a) 4
(b) 8
(c) 5
(d) 7
Show Answer & Explanation

Answer: (a) 4

Explanation:
1. Only the heterozygous gene pairs (Cc and Dd) give two kinds of alleles.
2. The number of gamete types is \( 2^2 = 4 \).

Teacher's Note:
1. Homozygous pairs do not add to the number of gamete types.

Question 12: The proportion of progeny with round seeds and red flowers, if a cross is made between WwRr and wwRr pea plants (W = round, R = red), is:
(a) 3/8
(b) 1/8
(c) 4/8
(d) 2/8
Show Answer & Explanation

Answer: (a) 3/8

Explanation:
1. For round seeds, Ww × ww gives 1/2 Ww.
2. For red flowers, Rr × Rr gives \( 3/4 R_ \).

Teacher's Note:
1. Multiplying \( 1/2 \times 3/4 \) gives 3/8.

Question 13: How many plants of genotype AabbCc are expected out of 256 seeds collected from the F2 of a trihybrid cross?
(a) 32
(b) 16
(c) 12
(d) 8
Show Answer & Explanation

Answer: (b) 16

Explanation:
1. P(Aa) = 1/2, P(bb) = 1/4 and P(Cc) = 1/2, so P(AabbCc) = 1/16.
2. Of 256 seeds, \( 256/16 = 16 \) plants are expected.

Teacher's Note:
1. Convert the genotype probability into numbers by multiplying with the total.

Question 14: The ratio of plants dominant for both characters to plants recessive for both characters in the F2 of a dihybrid cross is:
(a) 1 : 1
(b) 5 : 3
(c) 9 : 1
(d) 3 : 1
Show Answer & Explanation

Answer: (c) 9 : 1

Explanation:
1. The \( F2 \) ratio is 9 : 3 : 3 : 1.
2. Plants showing both dominant characters are 9 parts and those showing both recessive characters are 1 part.

Teacher's Note:
1. Hence the ratio is 9 : 1.

Question 15: Which of the following will NOT be a genotype of a pollen grain of a plant with genotype HHbbDdnnMMaa?
(a) HbdNMa
(b) HbDnMa
(c) Hbdnma
(d) All of these are possible
Show Answer & Explanation

Answer: (a) HbdNMa

Explanation:
1. Pollen grains are haploid and carry one allele of each gene.
2. The plant is nn, so it cannot make a gamete with \( N \).
3. The gamete HbdNMa is therefore impossible.

Teacher's Note:
1. Check each allele of the gamete against the parental genotype.

Question 16: What is the probability of gamete AbC produced by a plant of genotype AaBbCc (all genes on different chromosomes)?
(a) 1/2
(b) 1/4
(c) 1/6
(d) 1/8
Show Answer & Explanation

Answer: (d) 1/8

Explanation:
1. Each allele goes into a gamete with probability 1/2 for independent genes.
2. So P(AbC) = \( 1/2 \times 1/2 \times 1/2 = 1/8 \).

Teacher's Note:
1. Eight equally likely gamete types are formed, so each has probability 1/8.

Question 17: A plant has genotype TtRrGgPP. On selfing, the total number of phenotypic categories is:
(a) 8
(b) 16
(c) 4
(d) 27
Show Answer & Explanation

Answer: (a) 8

Explanation:
1. Three gene pairs are heterozygous (Tt, Rr, Gg), and PP is homozygous.
2. So there are \( 2^3 = 8 \) phenotypes with complete dominance.

Teacher's Note:
1. Homozygous pairs do not increase the number of phenotypes.

Question 18: The location of a particular gene on a sex chromosome or on an autosome can be identified by:
(a) Test cross
(b) Out cross
(c) Back cross
(d) Reciprocal cross
Show Answer & Explanation

Answer: (d) Reciprocal cross

Explanation:
1. In a reciprocal cross the sexes of the parents carrying each trait are interchanged.
2. Different results from the two crosses show sex linkage, while identical results show autosomal inheritance.

Teacher's Note:
1. A test cross only reveals the genotype.

Question 19: In a dihybrid cross RRTT (red, tall) × rrtt (white, dwarf), what is the ratio of red plants to tall plants in the F2 generation?
(a) 3 : 1
(b) 1 : 1
(c) 1 : 2
(d) 2 : 3
Show Answer & Explanation

Answer: (b) 1 : 1

Explanation:
1. In \( F2 \) the red plants are 12/16 and the tall plants are 12/16, so the ratio is 1 : 1.
2. Each character separately follows the monohybrid 3 : 1 ratio.

Teacher's Note:
1. Treat each character independently and compare the numbers.

Question 20: In a cross between two individuals of genotype AaBbccDdEeFf, the probability that an offspring will be heterozygous at all these genes is:
(a) 0
(b) 1/16
(c) 1/32
(d) 1/64
Show Answer & Explanation

Answer: (a) 0

Explanation:
1. The cross is cc × cc, which can only give cc offspring.
2. An offspring can therefore never be heterozygous for this gene.
3. So the overall probability is zero.

Teacher's Note:
1. One homozygous gene pair is enough to make the product zero.

Question 21: Offspring of which cross will be phenotypically and genotypically similar?
(a) Dd × Dd
(b) DD × dd
(c) DD × Dd
(d) Ww × Ww
Show Answer & Explanation

Answer: (b) DD × dd

Explanation:
1. DD × dd gives only Dd offspring, which are all alike in genotype and phenotype.
2. The other crosses produce more than one genotype.

Teacher's Note:
1. A cross between two different homozygotes gives a uniform \( F1 \).

Question 22: What is the phenotypic ratio of the F2 generation obtained by selfing an F1 plant of genotype AABbCC?
(a) 3 : 1
(b) 1 : 1
(c) 0 : 3 : 3 : 1
(d) 27 : 9 : 9 : 9 : 3 : 3 : 3 : 1
Show Answer & Explanation

Answer: (a) 3 : 1

Explanation:
1. Only one gene pair (Bb) is heterozygous, so selfing is a monohybrid cross.
2. The \( F2 \) ratio is 3 : 1.

Teacher's Note:
1. Homozygous gene pairs do not alter the ratio.

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