NEET Biology Cell Cycle and Cell Division MCQs Set 21

Multiple Choice Questions (MCQs) for NEET Biology: Cell Cycle and Cell Division

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Multiple Choice Questions

Question 1: A cell that is entering the mitotic phase (M-phase) of the cell cycle is :
(a) always haploid and with duplicated chromosomes
(b) either haploid or diploid and with duplicated chromosomes
(c) either haploid or diploid and with duplicated or unduplicated chromosomes
(d) always diploid and with unduplicated chromosomes
Show Answer & Explanation

Answer: (b) either haploid or diploid and with duplicated chromosomes

Explanation:
1. Mitosis can occur in haploid cells (for example in plants) as well as diploid cells.
2. Any cell entering M has already completed the S phase, so its chromosomes are duplicated.

Teacher's Note:
1. Ploidy does not decide whether a cell can undergo mitosis.
2. Duplication always precedes entry into M.

Question 2: How many chromatids does each chromosome have in the prophase of the cell cycle?
(a) 2
(b) 1
(c) 4
(d) 8
Show Answer & Explanation

Answer: (a) 2

Explanation:
1. Chromosomes were replicated in the S phase.
2. So every chromosome seen in prophase consists of two sister chromatids.

Teacher's Note:
1. Chromosomes are double-stranded from G2 until anaphase.
2. After anaphase each chromatid is called a chromosome.

Question 3: Synaptonemal complex is a nucleoprotein structure. It is visible or found from :
(a) zygotene to pachytene
(b) leptotene to diplotene
(c) zygotene to metaphase
(d) pachytene to diplotene
Show Answer & Explanation

Answer: (a) zygotene to pachytene

Explanation:
1. The complex starts forming in zygotene when homologues pair.
2. It is fully formed in pachytene and dissolves in diplotene.

Teacher's Note:
1. It holds paired homologues together during crossing over.
2. It is a feature of prophase I only.

Question 4: Which one of the following is correctly matched?
(a) Leptotene - formation of bivalents
(b) Diplotene - chiasmata appear
(c) Pachytene - terminalisation of chiasmata
(d) Zygotene - terminalisation of chiasmata
Show Answer & Explanation

Answer: (b) Diplotene - chiasmata appear

Explanation:
1. Chiasmata become visible in diplotene when the homologues begin to separate.
2. Bivalents form in zygotene, and terminalisation happens in diakinesis.

Teacher's Note:
1. Learn each prophase I sub-stage with its landmark event.
2. Leptotene, zygotene, pachytene, diplotene, diakinesis.

Question 5: In which stage of meiosis are the chromosomes thin, long and thread-like?
(a) Zygotene
(b) Leptotene
(c) Pachytene
(d) Diakinesis
Show Answer & Explanation

Answer: (b) Leptotene

Explanation:
1. Leptotene means thin thread.
2. Chromosomes begin to condense and appear as long slender threads.

Teacher's Note:
1. The name leptotene itself means thin threads.
2. Compaction increases through the later sub-stages.

Question 6: Meiosis involves :
(a) one nuclear division and one chromosome division
(b) two nuclear divisions and one chromosome division
(c) one nuclear division and two chromosome divisions
(d) two nuclear divisions and two chromosome divisions
Show Answer & Explanation

Answer: (b) two nuclear divisions and one chromosome division

Explanation:
1. The nucleus divides twice (meiosis I and II).
2. Chromosomes (DNA and centromeres) are divided only once, at anaphase II.

Teacher's Note:
1. Two nuclear divisions give four haploid nuclei.
2. Replication happens only once, before meiosis I.

Question 7: In meiosis, the centromeres of chromosomes divide during :
(a) anaphase of meiosis-II
(b) metaphase of meiosis-I
(c) anaphase of meiosis-I
(d) prophase of meiosis-II
Show Answer & Explanation

Answer: (a) anaphase of meiosis-II

Explanation:
1. In anaphase I whole chromosomes (with two chromatids) move apart.
2. The centromere splits only in anaphase II, separating the sister chromatids.

Teacher's Note:
1. Centromere division is absent in anaphase I.
2. This is the key difference from mitotic anaphase.

Question 8: Which of the following does not occur in anaphase I but occurs in anaphase II?
(a) Condensation of chromosomes
(b) Poleward movement of chromosomes
(c) Contraction of spindle fibres
(d) Splitting of the centromere
Show Answer & Explanation

Answer: (d) Splitting of the centromere

Explanation:
1. Anaphase I separates homologous chromosomes and the centromeres stay intact.
2. In anaphase II the centromeres split and sister chromatids separate.

Teacher's Note:
1. Poleward movement happens in both anaphases.
2. Only centromere splitting is exclusive to anaphase II.

Question 9: Crossing over takes place in :
(a) zygotene
(b) pachytene
(c) diplotene
(d) diakinesis
Show Answer & Explanation

Answer: (b) pachytene

Explanation:
1. Homologues are fully synapsed in pachytene.
2. Recombination nodules mediate exchange between non-sister chromatids at this stage.

Teacher's Note:
1. Crossing over needs complete synapsis.
2. Its result (chiasmata) becomes visible in diplotene.

Question 10: During cytokinesis, a contractile mid body forms in :
(a) animal cells
(b) higher plants
(c) fungi
(d) algae
Show Answer & Explanation

Answer: (a) animal cells

Explanation:
1. Animal cells divide by a furrow made by a contractile ring of actin and myosin.
2. The narrow bridge left at the end is the mid body.

Teacher's Note:
1. Plants form a cell plate instead of a furrow.
2. The rigid wall of plant cells prevents furrowing.

Question 11: In higher plants, cytokinesis proceeds :
(a) centripetally
(b) centrifugally
(c) obliquely
(d) equatorially
Show Answer & Explanation

Answer: (b) centrifugally

Explanation:
1. The cell plate starts forming at the centre from vesicles of Golgi.
2. It grows outward toward the cell wall, so cytokinesis is centrifugal.

Teacher's Note:
1. Animal furrow is centripetal (outside inward).
2. Plant cell plate is centrifugal (inside outward).

Question 12: Which two events restore the normal chromosome number in the life cycle?
(a) Mitosis and meiosis
(b) Meiosis and fertilisation
(c) Fertilisation and mitosis
(d) Only meiosis
Show Answer & Explanation

Answer: (b) Meiosis and fertilisation

Explanation:
1. Meiosis halves the chromosome number to form gametes.
2. Fertilisation restores the diploid number by fusing two gametes.

Teacher's Note:
1. Meiosis alone would keep reducing the number.
2. The two events balance each other every generation.

Question 13: Which part of a plant is suitable for the study of meiosis?
(a) Root apex
(b) Ovary
(c) Anther
(d) Shoot apex
Show Answer & Explanation

Answer: (c) Anther

Explanation:
1. Meiosis occurs in spore and gamete mother cells.
2. Young anthers contain many pollen mother cells dividing by meiosis, so they are used for squashes.

Teacher's Note:
1. Root and shoot apices show only mitosis.
2. The anther is the classic material for meiosis.

Question 14: Chromosomal movement in anaphase occurs with the help of :
(a) astral rays
(b) centrioles
(c) NOR
(d) spindle fibres
Show Answer & Explanation

Answer: (d) spindle fibres

Explanation:
1. Kinetochore microtubules of the spindle pull chromosomes toward the poles.
2. Astral rays only anchor the poles, and NOR is a nucleolar organiser region.

Teacher's Note:
1. Microtubules of the spindle do the pulling.
2. Remember kinetochore fibres attach at the centromere.

Question 15: Slipping of chiasmata towards the ends of the bivalent is called :
(a) terminalisation
(b) diakinesis
(c) interkinesis
(d) congression
Show Answer & Explanation

Answer: (a) terminalisation

Explanation:
1. Chiasmata move from their original position to the chromosome ends.
2. This process, terminalisation, occurs in diakinesis.

Teacher's Note:
1. Terminalisation is the process, diakinesis is the stage.
2. Congression is movement of chromosomes to the equator.

Question 16: Which of the following does not occur in prophase?
(a) Decondensation of chromatin
(b) Condensation of chromatin
(c) Appearance of chromosomes
(d) Disappearance of nuclear membrane and nucleolus
Show Answer & Explanation

Answer: (a) Decondensation of chromatin

Explanation:
1. Chromatin condenses into visible chromosomes in prophase.
2. Decondensation is a telophase event.

Teacher's Note:
1. Prophase builds up, telophase breaks down.
2. Condensation and decondensation are opposite events.

Question 17: In which stage of cell division can the number of chromosomes be counted best?
(a) Prophase
(b) Metaphase
(c) Telophase
(d) Interphase
Show Answer & Explanation

Answer: (b) Metaphase

Explanation:
1. Chromosomes are most condensed and lie in one plane at metaphase.
2. This makes counting and study of morphology easiest.

Teacher's Note:
1. Karyotypes are prepared from metaphase cells.
2. Colchicine is used to arrest cells at this stage.

Question 18: How many chromosomes are present in a diploid cell at mitotic anaphase if its egg cell has ten chromosomes?
(a) 10
(b) 20
(c) 30
(d) 40
Show Answer & Explanation

Answer: (d) 40

Explanation:
1. The egg is haploid, so n = 10 and the diploid number 2n = 20.
2. At anaphase the chromatids separate, doubling the chromosome number to 40.

Teacher's Note:
1. Anaphase temporarily doubles the number.
2. It returns to 2n after cytokinesis.

Question 19: Chromosomes show the highest level of coiling in which phase of karyokinesis?
(a) Prophase
(b) Metaphase
(c) Telophase
(d) Interphase
Show Answer & Explanation

Answer: (b) Metaphase

Explanation:
1. Condensation increases through prophase and is maximum at metaphase.
2. That is why metaphase chromosomes are best seen.

Teacher's Note:
1. Maximum coiling, maximum visibility.
2. Decondensation starts in telophase.

Question 20: In which stages of mitosis are the chromosomes made of two chromatids?
(a) Prophase and metaphase
(b) Anaphase and telophase
(c) Prophase and telophase
(d) Metaphase and anaphase
Show Answer & Explanation

Answer: (a) Prophase and metaphase

Explanation:
1. Chromosomes remain double until the centromere splits at the start of anaphase.
2. So prophase and metaphase chromosomes have two chromatids.

Teacher's Note:
1. Anaphase and telophase chromosomes are single chromatids.
2. The centromere split is the dividing line.

Question 21: The gap between the end of the division phase and the start of DNA replication is called :
(a) G1 phase
(b) G2 phase
(c) M phase
(d) interkinesis
Show Answer & Explanation

Answer: (a) G1 phase

Explanation:
1. After M phase the cell enters G1 before the S phase begins.
2. The G1 phase is the pre-DNA-synthesis gap.

Teacher's Note:
1. G2 comes after S, not before it.
2. Interkinesis is a meiotic gap with no DNA replication.

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