NEET Biology Cell Cycle and Cell Division MCQs Set 23

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Chapter-wise Objective Questions: Cell Cycle and Cell Division

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Multiple Choice Questions

Question 1: In meiosis, the division of centromere occurs during :
(a) interphase
(b) anaphase I
(c) anaphase II
(d) metaphase I
Show Answer & Explanation

Answer: (c) anaphase II

Explanation:
1. Centromeres split only when sister chromatids separate.
2. That happens in anaphase II of meiosis.

Teacher's Note:
1. Anaphase I separates homologues instead.
2. Same fact appears in several forms in exams.

Question 2: Which stage of the cell cycle is misleadingly called the resting phase?
(a) S phase
(b) Telophase
(c) Cytokinesis
(d) Interphase
Show Answer & Explanation

Answer: (d) Interphase

Explanation:
1. Interphase looks quiet under the microscope.
2. In fact the cell is highly active, growing and replicating DNA.

Teacher's Note:
1. Interphase is the most active metabolic phase.
2. It takes more than 95 percent of the cycle in many cells.

Question 3: The synaptonemal complex is characteristic of :
(a) mitotic chromosomes
(b) leptotene chromosomes
(c) paired meiotic chromosomes
(d) metaphase chromosomes
Show Answer & Explanation

Answer: (c) paired meiotic chromosomes

Explanation:
1. It is a protein scaffold between synapsed homologues.
2. It forms only in meiotic prophase I.

Teacher's Note:
1. No synapsis, no synaptonemal complex.
2. Mitosis lacks homologue pairing.

Question 4: During which stage does the chromosome number of a diploid cell become 4n in mitosis?
(a) G2
(b) Prophase
(c) Metaphase
(d) Anaphase
Show Answer & Explanation

Answer: (d) Anaphase

Explanation:
1. Chromosomes keep the number 2n through G2, prophase and metaphase.
2. Splitting of centromeres in anaphase doubles the number of chromosomes to 4n.

Teacher's Note:
1. The number doubles temporarily only in anaphase and telophase.
2. Do not confuse it with DNA content, which doubles in S phase.

Question 5: The division of the centromere in mitosis occurs in :
(a) prophase
(b) metaphase
(c) anaphase
(d) telophase
Show Answer & Explanation

Answer: (c) anaphase

Explanation:
1. Centromeres split lengthwise at the onset of anaphase.
2. This lets sister chromatids move to opposite poles.

Teacher's Note:
1. Anaphase starts with the centromere split.
2. The event is simultaneous for all chromosomes.

Question 6: Each chromosome is composed of one chromatid in :
(a) anaphase I
(b) anaphase II
(c) metaphase I
(d) metaphase II
Show Answer & Explanation

Answer: (b) anaphase II

Explanation:
1. Chromosomes of anaphase II are the separated sister chromatids.
2. Those of anaphase I, metaphase I and metaphase II still have two chromatids.

Teacher's Note:
1. Single-chromatid chromosomes appear after centromere split.
2. In meiosis this is only from anaphase II.

Question 7: If the number of bivalents is 8 at metaphase I, what is the number of chromosomes in the daughter cells after meiosis I and after meiosis II respectively?
(a) 8 and 4
(b) 4 and 4
(c) 8 and 8
(d) 16 and 8
Show Answer & Explanation

Answer: (c) 8 and 8

Explanation:
1. 8 bivalents mean n = 8 and 2n = 16.
2. Meiosis I halves the number to 8 per cell.
3. Meiosis II separates chromatids but does not change the number, so it remains 8.

Teacher's Note:
1. Reduction happens in meiosis I.
2. Meiosis II is like mitosis in terms of number.

Question 8: Which one of the following statements is correct?
(a) Cells divide by cytokinesis only in mitosis
(b) DNA is replicated only before the start of meiosis
(c) Spindles of microtubules are formed only in mitosis
(d) Exchange of genetic material occurs only in meiosis
Show Answer & Explanation

Answer: (d) Exchange of genetic material occurs only in meiosis

Explanation:
1. Cytokinesis and spindle formation occur in both divisions, and mitosis also has DNA replication.
2. Crossing over (exchange between non-sister chromatids) is a feature of meiotic prophase I.

Teacher's Note:
1. Eliminate options with the word only one by one.
2. Recombination is the hallmark of meiosis.

Question 9: In meiosis :
(a) nucleus divides twice but DNA replicates only once
(b) nucleus divides twice and DNA replicates twice
(c) nucleus divides once and DNA replicates once
(d) nucleus divides once and DNA replicates twice
Show Answer & Explanation

Answer: (a) nucleus divides twice but DNA replicates only once

Explanation:
1. Meiosis I and II are two nuclear divisions.
2. The S phase occurs only once, before meiosis I.

Teacher's Note:
1. No S phase in interkinesis.
2. This is why the number of chromosomes ends up halved.

Question 10: After meiosis I, the two chromatids of a chromosome are :
(a) genetically similar
(b) genetically different
(c) present as only one chromatid per chromosome
(d) none of the above
Show Answer & Explanation

Answer: (b) genetically different

Explanation:
1. Crossing over exchanges segments between non-sister chromatids.
2. The two chromatids of a chromosome therefore carry different alleles.

Teacher's Note:
1. Sister chromatids are identical only if no crossing over occurred.
2. This is the source of variation.

Question 11: Chiasmata appear during :
(a) diakinesis
(b) synaptotene
(c) diplotene
(d) leptotene
Show Answer & Explanation

Answer: (c) diplotene

Explanation:
1. The synaptonemal complex dissolves in diplotene.
2. Homologues start separating and chiasmata, the sites of crossing over, become visible as X-shapes.

Teacher's Note:
1. Chiasmata are visible from diplotene.
2. They move to the ends in diakinesis.

Question 12: Reappearance of the nuclear membrane and nucleolus along with thinning and elongation of chromosomes are diagnostic characters of the phase :
(a) anaphase
(b) metaphase
(c) interphase
(d) telophase
Show Answer & Explanation

Answer: (d) telophase

Explanation:
1. Telophase reverses the changes of prophase.
2. The nuclear envelope and nucleolus reform and chromosomes decondense.

Teacher's Note:
1. Telophase is the reverse of prophase.
2. Cytokinesis usually follows.

Question 13: Condensation of chromosomes and appearance of astral rays occur during :
(a) prophase
(b) metaphase
(c) anaphase
(d) telophase
Show Answer & Explanation

Answer: (a) prophase

Explanation:
1. Chromatin condenses and centrosomes move apart forming asters in prophase.
2. This is the first stage of karyokinesis.

Teacher's Note:
1. Prophase is the build-up phase.
2. Asters are absent in higher plants.

Question 14: During telophase :
(a) the nuclear membrane is formed
(b) the nucleolus appears
(c) astral rays disappear
(d) all of the above
Show Answer & Explanation

Answer: (d) all of the above

Explanation:
1. Nuclear envelopes reform around the two sets of chromosomes.
2. Nucleoli reappear and the spindle and asters disassemble.

Teacher's Note:
1. Telophase mirrors prophase.
2. All three events happen together.

Question 15: Pairing of homologous chromosomes is called :
(a) disjunction
(b) synapsis
(c) segregation
(d) polyteny
Show Answer & Explanation

Answer: (b) synapsis

Explanation:
1. Pairing of homologues takes place in zygotene.
2. The paired structure is a bivalent.

Teacher's Note:
1. Synapsis forms bivalents.
2. Disjunction is the separation later in anaphase I.

Question 16: The correct sequence of the sub-stages of prophase I of meiosis is :
(a) leptotene, pachytene, zygotene, diplotene, diakinesis
(b) leptotene, diplotene, pachytene, zygotene, diakinesis
(c) leptotene, zygotene, pachytene, diplotene, diakinesis
(d) leptotene, zygotene, diakinesis, diplotene
Show Answer & Explanation

Answer: (c) leptotene, zygotene, pachytene, diplotene, diakinesis

Explanation:
1. The order follows chromosome behaviour: thin threads, pairing, crossing over, chiasmata, terminalisation.
2. That gives leptotene, zygotene, pachytene, diplotene, diakinesis.

Teacher's Note:
1. Use the mnemonic LZPDD for the order.
2. Prophase I is the longest phase of meiosis.

Question 17: The M-phase of the cell cycle consists of :
(a) G1, S and G2 phases
(b) prophase, metaphase, anaphase and telophase
(c) interphase, prophase, metaphase, anaphase and telophase
(d) only prophase
Show Answer & Explanation

Answer: (b) prophase, metaphase, anaphase and telophase

Explanation:
1. The M-phase is the actual division, covering the four stages of karyokinesis.
2. G1, S and G2 belong to interphase.

Teacher's Note:
1. Interphase is separate from M-phase.
2. Cytokinesis usually completes M-phase.

Question 18: The pre-DNA synthesis phase is :
(a) G1 phase
(b) G2 phase
(c) S phase
(d) prophase
Show Answer & Explanation

Answer: (a) G1 phase

Explanation:
1. G1 comes before the S phase.
2. G2 is the post-DNA-synthesis phase.

Teacher's Note:
1. Pre means before S.
2. G2 is also called the pre-mitotic phase.

Question 19: Which of the following is called heterotypic division?
(a) Meiosis I
(b) Meiosis II
(c) Mitosis
(d) Amitosis
Show Answer & Explanation

Answer: (a) Meiosis I

Explanation:
1. Meiosis I reduces the chromosome number from 2n to n, so it is a reduction division.
2. It is therefore called heterotypic division, while meiosis II is homotypic.

Teacher's Note:
1. Heterotypic means reductional.
2. Meiosis II and mitosis are equational.

Question 20: DNA replication is found in :
(a) mitosis and meiosis I
(b) mitosis, meiosis I and meiosis II
(c) meiosis only
(d) mitosis only
Show Answer & Explanation

Answer: (a) mitosis and meiosis I

Explanation:
1. Both divisions are preceded by an S phase (before mitosis and before meiosis I).
2. There is no replication before meiosis II.

Teacher's Note:
1. Interkinesis has no S phase.
2. Replication is once per cycle.

Question 21: The thick-thread stage occurs in :
(a) leptotene
(b) zygotene
(c) pachytene
(d) diplotene
Show Answer & Explanation

Answer: (c) pachytene

Explanation:
1. Bivalents become shorter and thicker in pachytene.
2. Each bivalent shows four chromatids, a tetrad.

Teacher's Note:
1. Pachytene means thick thread.
2. Crossing over occurs in this stage.

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