NEET Biology Cell Cycle and Cell Division MCQs Set 12

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Chapter-wise Objective Questions: Cell Cycle and Cell Division

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Multiple Choice Questions

Question 1: Arrange the following events of meiosis in the correct sequence: (A) Terminalisation of chiasmata, (B) Crossing over, (C) Synapsis, (D) Disjunction of homologous chromosomes, (E) Dissociation of the synaptonemal complex.
(a) A → B → C → D → E
(b) E → D → C → B → A
(c) C → B → D → E → A
(d) C → B → E → A → D
Show Answer & Explanation

Answer: (d) C → B → E → A → D

Explanation:
1. Prophase I proceeds through leptotene, zygotene (synapsis, C), pachytene (crossing over, B), diplotene (dissociation of the synaptonemal complex, E) and diakinesis (terminalisation of chiasmata, A).
2. Disjunction of homologous chromosomes (D) occurs afterwards, in anaphase I. The sequence is C, B, E, A, D.

Teacher's Note:
1. Mnemonic: leptotene, zygotene, pachytene, diplotene, diakinesis.
2. Chiasmata are visible in diplotene and move toward the ends in diakinesis.

Question 2: The graph shows the changes in DNA content during various phases (A to D) in a typical cell: A is flat at 2C, B rises from 2C to 4C, C is flat at 4C and D falls from 4C to 2C. Identify the phases A, B, C and D respectively:
DNA content Time 4C 2C A B C D (a) G₂, G₁, S, M
(b) M, G₂, S, G₁
(c) G₁, S, G₂, M
(d) M, G₁, S, G₂
Show Answer & Explanation

Answer: (c) G₁, S, G₂, M

Explanation:
1. DNA stays at 2C during G₁ (A).
2. DNA doubles from 2C to 4C during the S phase (B).
3. DNA stays at 4C during G₂ (C).
4. DNA content falls back from 4C to 2C at the M phase (D), when the cell divides.

Teacher's Note:
1. S phase = DNA synthesis, so the rising part of the graph.
2. The fall in DNA content marks cell division (M).

Question 3: Which of the following events does not occur in mitosis?
(a) Attachment of spindle fibres to the chromosomes
(b) Reformation of the nuclear envelope
(c) Formation of the synaptonemal complex
(d) Splitting of the centromere
Show Answer & Explanation

Answer: (c) Formation of the synaptonemal complex

Explanation:
1. The synaptonemal complex forms during zygotene of prophase I of meiosis, when homologous chromosomes pair.
2. In mitosis there is no pairing of homologues; spindle attachment, nuclear envelope reformation (telophase) and centromere splitting (anaphase) all occur.

Teacher's Note:
1. Synapsis is exclusive to meiosis.
2. Mitosis is an equational division.

Question 4: ____ I ____ division ensures the production of the haploid phase in the life cycle of sexually reproducing organisms, whereas ____ II ____ restores the diploid phase. Choose the correct words for I and II:
(a) Mitosis, Meiosis
(b) Mitosis, Amitosis
(c) Amitosis, Meiosis
(d) Meiosis, Fertilisation
Show Answer & Explanation

Answer: (d) Meiosis, Fertilisation

Explanation:
1. Meiosis halves the chromosome number and produces haploid cells (gametes or spores).
2. Fertilisation, the fusion of two haploid gametes, restores the diploid phase.

Teacher's Note:
1. Meiosis and fertilisation keep the chromosome number constant across generations.
2. Mitosis keeps the same chromosome number in daughter cells.

Question 5: When karyokinesis is not followed by cytokinesis, it results in the formation of:
(a) polyploid cells
(b) polytene chromosomes
(c) lampbrush chromosomes
(d) multinucleated cells
Show Answer & Explanation

Answer: (d) multinucleated cells

Explanation:
1. Karyokinesis is the division of the nucleus and cytokinesis is the division of the cytoplasm.
2. If the cytoplasm does not divide, the daughter nuclei stay in one cell, which becomes multinucleate (as in the coenocytic endosperm of coconut).

Teacher's Note:
1. Liquid endosperm of coconut is a standard example.
2. Do not confuse this with polyploidy, which is a change in chromosome sets.

Question 6: During the cell cycle, DNA polymerase activity and histone protein synthesis occur in:
(a) G₀
(b) G₁
(c) S phase
(d) G₂
Show Answer & Explanation

Answer: (c) S phase

Explanation:
1. DNA replication happens in the S phase, so DNA polymerase is active then.
2. Histones are needed to package the new DNA, so they are also synthesised in the S phase.

Teacher's Note:
1. S phase is the synthesis phase.
2. G₁ cells are metabolically active but do not replicate DNA.

Question 7: If a cell has 20 pg of DNA in the G₂ phase, what will be the amount of DNA in each daughter cell after meiosis I?
(a) 10 pg
(b) 20 pg
(c) 40 pg
(d) 5 pg
Show Answer & Explanation

Answer: (a) 10 pg

Explanation:
1. G₂ cells have already replicated their DNA (4C = 20 pg).
2. Meiosis I separates homologous chromosomes and gives two cells, each with half the DNA, so each daughter cell has 10 pg (2C).

Teacher's Note:
1. DNA content halves at meiosis I and halves again at meiosis II.
2. Each daughter cell after meiosis II would have 5 pg.

Cell Cycle and Cell Division Objective Questions & Solutions for NEET Biology

NEET Biology Cell Cycle and Cell Division Objective Test Questions

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