NEET Biology Biomolecules MCQs Set 10

Multiple Choice Questions (MCQs) for NEET Biology: Biomolecules

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Practice Biomolecules MCQs for NEET Biology

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Multiple Choice Questions

Question 1: Which of the following pairs of nitrogenous bases of nucleic acids is mismatched with the category mentioned against it?
(a) Adenine, Thymine – Purines
(b) Thymine, Uracil – Pyrimidines
(c) Uracil, Cytosine – Pyrimidines
(d) Guanine, Adenine – Purines
Show Answer & Explanation

Answer: (a) Adenine, Thymine – Purines

Explanation:
1. Adenine and Guanine → Purines Thymine, uracil, cytosine → Pyrimidines.

Question 2: In a DNA molecule
(a) There are two strands which run antiparallel-one in 5′ → 3′ direction and other in 3′ → 5′
(b) The total amount of purine nucleotides and pyrimidine nucleotides is not always equal
(c) There are two strands which run parallel in the 5′ → 3′ direction
(d) The proportion of adenine in relation to thymine varies with the organism
Show Answer & Explanation

Answer: (a) There are two strands which run antiparallel-one in 5′ → 3′ direction and other in 3′ → 5′

Explanation:
1. In DNA, two antiparallel strands are coiled around a common axis.

Question 3: Which purine base is found in RNA?
(a) Thymine
(b) Uracil
(c) Cytosine
(d) Guanine
Show Answer & Explanation

Answer: (d) Guanine

Explanation:
1. This is so because thymine → Present in DNA, not in RNA Cytosine, uracil → Pyrimidine.

Question 4: Which of the following enzymes is used to join bits of DNA?
(a) Ligase
(b) Primase
(c) DNA polymerase
(d) Endonuclease
Show Answer & Explanation

Answer: (a) Ligase

Explanation:
1. Class VI → Ligase enzyme is used to join the bits of DNA. Primase → Is an enzyme use to attach primer.
2. DNA polymerase → is an enzyme use to add nucleotide in template strand of DNA. Endonuclease → It is an restriction enzyme which causes internal cleavage of DNA.

Question 5: ATP is
(a) Nucleotide
(b) Nucleoside
(c) Nucleic acid
(d) Vitamin
Show Answer & Explanation

Answer: (a) Nucleotide

Explanation:
1. This is so because ATP (Adenosine triphosphate) is made up of adenine, ribose sugar and 3 phosphate groups.

Question 6: The role of an enzyme in a reaction is to/as
(a) Decrease activation energy
(b) Increase activation energy
(c) Inorganic catalyst
(d) None of these
Show Answer & Explanation

Answer: (a) Decrease activation energy

Explanation:
1. Potential Transition state energy Activation energy without enzyme Activation energy with enzyme Substrate energy Product Progress of reaction.

Question 7: Which of the following factor(s) do(es) not affect enzyme activity?<br />A. Temperature B. pH<br />C. Enzyme concentration D. Product concentration<br />E. Substrate concentration F. Activation energy
(a) C only
(b) C & D
(c) D only
(d) F only
Show Answer & Explanation

Answer: (d) F only

Explanation:
1. This is so because enzyme activity is affected by temperature, pH, enzyme concentration, product concentration and substrate concentration.
2. Enzyme are not affected by activation energy but it lowers down the activation energy.

Question 8: A competitive inhibitor of succinic dehydrogenase is
(a) Malate
(b) Malonate
(c) Oxaloacetate
(d) Both (2) & (3)
Show Answer & Explanation

Answer: (d) Both (2) & (3)

Explanation:
1. Competitive inhibitors of succinic dehydrogenase are malate, malonate, oxaloacetate.

Question 9: Which of the following is a typical example of ‘feedback inhibition’?
(a) Cyanide and cytochrome reaction
(b) Sulpha drugs and folic acid synthesizer bacteria
(c) Allosteric inhibition of hexokinase by glucose 6-phosphate
(d) Reaction between succinic dehydrogenase and succinic acid
Show Answer & Explanation

Answer: (c) Allosteric inhibition of hexokinase by glucose 6-phosphate

Explanation:
1. (1) Cyanide and cytochrome reaction → Example of non-competitive inhibition. (2) Sulpha drugs and folic acid synthesizer bacteria are example of non-competitive inhibition. (4) Reaction between succinic dehydrogenase and succinic acid are example of competitive inhibition.

Question 10: Which factor is responsible for inhibition of enzymatic process during feedback?
(a) Substrate
(b) Enzyme
(c) End product
(d) Temperature
Show Answer & Explanation

Answer: (c) End product

Explanation:
1. Feedback inhibition is also konwn as End product inhibition or allosteric modulation.

Question 11: Which of the following is true for competitive enzyme inhibition?
(a) Decrease in Vmax and Km
(b) Unchanged Vmax and decrease in Km
(c) Unchanged Vmax and increase in Km
(d) Increase in Vmax and Km
Show Answer & Explanation

Answer: (c) Unchanged Vmax and increase in Km

Explanation:
1. Vmax = constant; Km = increased Vmax No Inhibitor With inhibitor Reaction velocity Vmax 2 Km K'm [S].

Question 12: The Michaelis constant Km is
(a) Numerically equal to ½ Vmax
(b) Dependent on the enzyme concentration
(c) Numerically equal to the substrate concentration that gives half maximal velocity
(d) Increased in the presence of non-competitive inhibitor
Show Answer & Explanation

Answer: (c) Numerically equal to the substrate concentration that gives half maximal velocity

Explanation:
1. vmax Velocity vmax of reaction 2 Km [s].

Question 13: Prosthetic group is a part of holoenzyme. It is
(a) Loosely attached organic part
(b) Loosely attached inorganic part
(c) Non-protein organic part firmly attached with apoenzyme
(d) None of these
Show Answer & Explanation

Answer: (c) Non-protein organic part firmly attached with apoenzyme

Explanation:
1. Enzyme (Holoenzyme) Protein Non-protein (Apoenzyme) (Cofactor) Organic compound Inorganic compound It includes metal ions 2+ 2+ 2+ Tightly bound Loosely bound i.e., Zn , Mg , Ca etc. (Prosthetic group).

Question 14: Mark the mismatched pair.
(a) Cellulose : Unbranched polymer with β,1-4 glycosidic linkage
(b) Cellophane : Cellulose xanthate
(c) Carboxypeptidase : Exopeptidase, Mg2+ acts as a co-factor
(d) Aminopeptidase : Exopeptidase, cleaves the peptide bond at N-terminal end
Show Answer & Explanation

Answer: (c) Carboxypeptidase : Exopeptidase, Mg2+ acts as a co-factor

Explanation:
1. Carboxypeptidase requires Zn2+ as cofactor.

Question 15: Apoenzyme is
(a) Always a protein
(b) Often a metal
(c) Always an inorganic compound
(d) Often a vitamin
Show Answer & Explanation

Answer: (a) Always a protein

Explanation:
1. Protein part of enzyme is known as apoenzyme and non-protein part of enzyme is known as cofactor.

Question 16: Assertion (A): Cofactor of an enzyme may be a prosthetic group.
Reason (R): NAD derived from niacin is a co-enzyme.
(a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.
(b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
(c) Assertion is true but the Reason is false.
(d) Both Assertion and Reason are false.
Show Answer & Explanation

Answer: (b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.

Explanation:
1. Organic compound firmly attach to protein part of enzyme is prosthetic group.

Question 17: Assertion (A): Tertiary structure of protein molecules makes them biologically active.
Reason (R): It is native configuration of protein molecules maintained by multiple covalent bonds only.
(a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.
(b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
(c) Assertion is true but the Reason is false.
(d) Both Assertion and Reason are false.
Show Answer & Explanation

Answer: (c) Assertion is true but the Reason is false.

Explanation:
1. This is so because enzyme exists in tertiary structure in which sides group comes close and form an active site.

Question 18: Assertion (A): Non-competitive inhibitors have no effect on Vmax.
Reason (R): In non-competitive inhibition, inhibitor and substrate bind at same sites on the enzyme.
(a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.
(b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
(c) Assertion is true but the Reason is false.
(d) Both Assertion and Reason are false.
Show Answer & Explanation

Answer: (d) Both Assertion and Reason are false.

Explanation:
1. Non-competitive inhibitors decrease Vmax.

Question 19: Assertion (A): The polypeptide coil of collagen helix is strengthened by the estabilishment of hydrogen bond between > NH - group of glycine residue of each strand with –CO group of other two strand.
Reason (R): In collagen helix locking effect also occurs with the help of proline and hydroxyproline amino acid.
(a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.
(b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
(c) Assertion is true but the Reason is false.
(d) Both Assertion and Reason are false.
Show Answer & Explanation

Answer: (b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.

Explanation:
1. In collagen, there are generally three polypeptides coil around one another.

Question 20: Assertion (A): Allosteric enzymes do not show a typical Michaelis Menten constant or behaviour.
Reason (R): All enzymes work at same pH.
(a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.
(b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
(c) Assertion is true but the Reason is false.
(d) Both Assertion and Reason are false.
Show Answer & Explanation

Answer: (c) Assertion is true but the Reason is false.

Explanation:
1. Allosteric enzymes don't obey Michaelis Menten constant.

Question 21: Assertion (A): α amylase of wheat endosperm has 16 isoenzymes.
Reason (R): In competitive inhibition Vmax decreases.
(a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.
(b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
(c) Assertion is true but the Reason is false.
(d) Both Assertion and Reason are false.
Show Answer & Explanation

Answer: (c) Assertion is true but the Reason is false.

Explanation:
1. Isoenzymes are the isomeric form of same enzyme.

Question 22: Assertion (A): Tertiary structure of protein is absolutely necessary for many biological activities of proteins.
Reason (R): In protein, only right handed helices are observed.
(a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.
(b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
(c) Assertion is true but the Reason is false.
(d) Both Assertion and Reason are false.
Show Answer & Explanation

Answer: (b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.

Explanation:
1. Enzymes have tertiary structure of protein.

Multiple Choice Questions (MCQs) for NEET Biology Biomolecules

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