NEET Biology Cell Cycle and Cell Division MCQs Set 06

Multiple Choice Questions (MCQs) for NEET Biology: Cell Cycle and Cell Division

Review structured MCQ sets for NEET Biology Cell Cycle and Cell Division. Built according to official NEET guidelines, these downloadable questions support daily revision and core concept reinforcement.

Practice Cell Cycle and Cell Division MCQs for NEET Biology

Access the complete set of multiple-choice questions for Cell Cycle and Cell Division below. This focused format allows students to isolate specific topics for thorough review and uninterrupted practice alongside official NEET textbooks.

Multiple Choice Questions

Question 1: What is the number of chromosome pairs at the equator in metaphase I of a diploid plant cell with n = 25?
(a) 50
(b) 100
(c) 75
(d) 25
Show Answer & Explanation

Answer: (d) 25

Explanation:
1. 2n = 50, which form 25 homologous pairs (bivalents).
2. All 25 bivalents lie at the equator in metaphase I.

Teacher's Note:
1. Number of bivalents equals n.
2. Chromosomes are 50 and chromatids 100.

Question 2: How many meiotic divisions are required to form 500 zygotes, if in males one meiotic division gives four gametes and in females one meiotic division gives one gamete?
(a) 625
(b) 500
(c) 1000
(d) 2500
Show Answer & Explanation

Answer: (a) 625

Explanation:
1. 500 zygotes need 500 sperm and 500 eggs.
2. 500 sperm need 125 meioses (4 per meiosis) and 500 eggs need 500 meioses.
3. Total = 125 + 500 = 625.

Teacher's Note:
1. Males give four gametes, females one.
2. Add the two separately.

Question 3: The number of chromatids in each chromosome at anaphase is :
(a) one in mitosis, one in meiosis I and two in meiosis II
(b) one in mitosis, two in meiosis I and one in meiosis II
(c) two in mitosis, one in meiosis I and two in meiosis II
(d) two in mitosis, two in meiosis I and two in meiosis II
Show Answer & Explanation

Answer: (b) one in mitosis, two in meiosis I and one in meiosis II

Explanation:
1. In mitosis and meiosis II the centromere splits, so each chromosome has one chromatid.
2. In anaphase I the centromere does not split and each chromosome has two chromatids.

Teacher's Note:
1. Mitotic anaphase and anaphase II are alike.
2. Anaphase I is the exception.

Question 4: If a cell had the diploid (2n) number of chromosomes at G1, what is the number of chromosomes in the cell after S phase?
(a) 2n
(b) 4n
(c) n
(d) 3n
Show Answer & Explanation

Answer: (a) 2n

Explanation:
1. DNA replication produces sister chromatids but they stay joined at the centromere.
2. The chromosome number therefore remains 2n.

Teacher's Note:
1. Count chromosomes by centromeres.
2. Only DNA content becomes 4C.

Question 5: During meiosis, how many cycles of nuclear division, DNA replication and division of centromere take place respectively?
(a) three, two, one
(b) one, two, two
(c) two, two, one
(d) two, one, one
Show Answer & Explanation

Answer: (d) two, one, one

Explanation:
1. The nucleus divides twice.
2. DNA replicates once (before meiosis I) and centromeres divide once (anaphase II).

Teacher's Note:
1. Two divisions, one replication, one centromere division.
2. Same fact as beginner questions on meiosis.

Question 6: Which of the following graphs shows the change in DNA content during the cell cycle for mitosis (A) and meiosis (B)? Graph A shows DNA rising once and falling once back to the starting level; graph B shows DNA rising once and then falling in two steps.
Amount of DNACell cycle(A)Amount of DNACell cycle(B) (a) A is meiosis II, B is meiosis I
(b) A is mitosis, B is meiosis I
(c) A is meiosis I, B is mitosis
(d) A is mitosis, B is meiosis
Show Answer & Explanation

Answer: (d) A is mitosis, B is meiosis

Explanation:
1. In mitosis DNA doubles in S and returns to the starting level after one division, as in graph A.
2. In meiosis DNA doubles once and falls in two steps (meiosis I, then II), as in graph B.

Teacher's Note:
1. One rise and one fall means mitosis.
2. One rise and two falls means meiosis.

Question 7: Assertion (A): Cells in the quiescent stage (G0) are metabolically inactive, so they do not show cell division.
Reason (R): The quiescent stage appears when the cell exits from the G2 phase of the cell cycle.
(a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.
(b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
(c) Assertion is true but the Reason is false.
(d) Both Assertion and Reason are false.
Show Answer & Explanation

Answer: (d) Both Assertion and Reason are false.

Explanation:
1. G0 cells are metabolically active but not dividing, so the assertion is false.
2. The G0 stage is entered from G1, not G2, so the reason is also false.

Teacher's Note:
1. G0 cells are quiet but not dead.
2. They leave the cycle from G1.

Question 8: Assertion (A): Disappearance of the nuclear membrane is generally essential for karyokinesis.
Reason (R): Forward movement of chromosomes depends on the spindle apparatus, which is organised in the cytoplasm.
(a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.
(b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
(c) Assertion is true but the Reason is false.
(d) Both Assertion and Reason are false.
Show Answer & Explanation

Answer: (a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.

Explanation:
1. The spindle forms in the cytoplasm and must reach the chromosomes, so the envelope must break down.
2. This is why both statements are true, and the reason explains the assertion.

Teacher's Note:
1. Spindle outside, chromosomes inside: the envelope must go.
2. Exceptions occur in some protists.

Question 9: Assertion (A): The morphology of chromosomes is most studied during metaphase of cell division.
Reason (R): Complete disintegration of the nuclear envelope marks the start of metaphase, the second phase of mitosis.
(a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.
(b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
(c) Assertion is true but the Reason is false.
(d) Both Assertion and Reason are false.
Show Answer & Explanation

Answer: (b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.

Explanation:
1. Chromosomes are most condensed and easily visible in metaphase, so the assertion is true.
2. The reason is also true, but it does not explain why morphology is best studied then.

Teacher's Note:
1. Both statements are facts but unrelated causally.
2. Condensation is the real reason.

Question 10: Assertion (A): The kinetochore is essential for cell division.
Reason (R): Kinetochores serve as sites of attachment of spindle fibres to chromosomes.
(a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.
(b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
(c) Assertion is true but the Reason is false.
(d) Both Assertion and Reason are false.
Show Answer & Explanation

Answer: (a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.

Explanation:
1. Without kinetochores spindle fibres cannot attach to chromosomes.
2. So chromosomes cannot be moved and division fails.

Teacher's Note:
1. Kinetochore equals attachment site.
2. Both statements are true and linked.

Question 11: Assertion (A): In anaphase the number of chromosomes gets doubled.
Reason (R): During anaphase each chromosome splits simultaneously and the two daughter chromatids are now referred to as chromosomes.
(a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.
(b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
(c) Assertion is true but the Reason is false.
(d) Both Assertion and Reason are false.
Show Answer & Explanation

Answer: (a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.

Explanation:
1. Centromere splitting converts each chromosome into two single-chromatid chromosomes.
2. So the number doubles, and the reason explains this.

Teacher's Note:
1. Count of centromeres equals count of chromosomes.
2. Doubling is temporary.

Question 12: Assertion (A): Cell growth results in division.
Reason (R): Cell growth leads to a change in the nucleocytoplasmic ratio.
(a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.
(b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
(c) Assertion is true but the Reason is false.
(d) Both Assertion and Reason are false.
Show Answer & Explanation

Answer: (a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.

Explanation:
1. As the cell grows, its nuclear volume relative to cytoplasm falls (karyoplasmic index decreases).
2. The nucleus can no longer control the cytoplasm, and this triggers division.

Teacher's Note:
1. Growth upsets the nucleus-cytoplasm balance.
2. Division restores it.

Question 13: Assertion (A): Meiosis I is the most significant phenomenon from the point of view of evolution.
Reason (R): Meiosis I leads to a reduction in chromosome number so that the constancy of chromosome number can be maintained.
(a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.
(b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
(c) Assertion is true but the Reason is false.
(d) Both Assertion and Reason are false.
Show Answer & Explanation

Answer: (b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.

Explanation:
1. Meiosis I has crossing over and independent assortment, which create variation for evolution.
2. The reason is true but concerns chromosome number constancy, not variation.

Teacher's Note:
1. Evolution depends on variation.
2. Reduction maintains number, not variation.

Question 14: Assertion (A): Zygotene is characterised by the formation of the synaptonemal complex.
Reason (R): The synaptonemal complex helps in synapsis of non-homologous chromosomes.
(a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.
(b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
(c) Assertion is true but the Reason is false.
(d) Both Assertion and Reason are false.
Show Answer & Explanation

Answer: (c) Assertion is true but the Reason is false.

Explanation:
1. The synaptonemal complex begins to form in zygotene, so the assertion is true.
2. It helps synapsis of homologous (not non-homologous) chromosomes, so the reason is false.

Teacher's Note:
1. Synapsis is between homologues only.
2. Watch for homologous and non-homologous swaps.

Question 15: Assertion (A): Each chromatid is attached with two spindle fibres during S phase.
Reason (R): During anaphase I each chromosome is found in bivalent form.
(a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.
(b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
(c) Assertion is true but the Reason is false.
(d) Both Assertion and Reason are false.
Show Answer & Explanation

Answer: (d) Both Assertion and Reason are false.

Explanation:
1. Spindle fibres are not attached during S phase, so the assertion is false.
2. Bivalents are present in metaphase I and separate into single chromosomes in anaphase I, so the reason is false.

Teacher's Note:
1. Spindle attachment is a metaphase feature.
2. Bivalents separate in anaphase I.

Question 16: Assertion (A): Replication of DNA does not occur during interkinesis.
Reason (R): Division of chromosomes (centromeres) takes place during meiosis II.
(a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.
(b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
(c) Assertion is true but the Reason is false.
(d) Both Assertion and Reason are false.
Show Answer & Explanation

Answer: (b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.

Explanation:
1. Interkinesis has no S phase, so the assertion is true.
2. The centromere does divide in meiosis II, so the reason is true, but it is not the reason for no replication.

Teacher's Note:
1. Both are true but unrelated.
2. The reason concerns anaphase II.

Question 17: Assertion (A): Meiosis is also known as reduction division.
Reason (R): Meiosis reduces the number of chromosomes in daughter cells.
(a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.
(b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
(c) Assertion is true but the Reason is false.
(d) Both Assertion and Reason are false.
Show Answer & Explanation

Answer: (a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.

Explanation:
1. Meiosis halves the chromosome number from 2n to n.
2. That is precisely why it is called reduction division.

Teacher's Note:
1. The name comes from the function.
2. Meiosis I is the reductional step.

Question 18: Assertion (A): Crossing over takes place during the pachytene stage.
Reason (R): It is a process of interchange of chromatid material between non-sister chromatids of homologous chromosomes.
(a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.
(b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
(c) Assertion is true but the Reason is false.
(d) Both Assertion and Reason are false.
Show Answer & Explanation

Answer: (b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.

Explanation:
1. Crossing over occurs in pachytene, and the reason correctly defines crossing over.
2. The definition does not explain why it occurs specifically in pachytene.

Teacher's Note:
1. The reason defines the process but does not explain the timing.
2. Pachytene has fully paired homologues.

Question 19: Assertion (A): Yeast can progress through the cell cycle in only about 90 minutes.
Reason (R): The duration of the cell cycle can vary from organism to organism.
(a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.
(b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
(c) Assertion is true but the Reason is false.
(d) Both Assertion and Reason are false.
Show Answer & Explanation

Answer: (b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.

Explanation:
1. Both statements are true.
2. The second is a general statement that does not specifically explain why yeast takes 90 minutes.

Teacher's Note:
1. Human cells take about 24 hours.
2. Cycle duration varies with organism and cell type.

Question 20: Assertion (A): M-phase is the most dramatic period of the cell cycle.
Reason (R): It involves a major reorganisation of virtually all components of the cell.
(a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.
(b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
(c) Assertion is true but the Reason is false.
(d) Both Assertion and Reason are false.
Show Answer & Explanation

Answer: (a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.

Explanation:
1. The nucleus, cytoskeleton and organelles are all rearranged in M phase.
2. This reorganisation is why it is called dramatic.

Teacher's Note:
1. Dramatic equals major reorganisation.
2. It lasts only about an hour in a human cell.

Question 21: Assertion (A): Small cells are metabolically less active.
Reason (R): The karyoplasmic index (K.I.) of small cells is less.
(a) Both Assertion and Reason are true and the Reason is a correct explanation of the Assertion.
(b) Both Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
(c) Assertion is true but the Reason is false.
(d) Both Assertion and Reason are false.
Show Answer & Explanation

Answer: (d) Both Assertion and Reason are false.

Explanation:
1. Small cells have a high karyoplasmic index and the nucleus controls their cytoplasm efficiently, so they are not less active.
2. Both statements are false.

Teacher's Note:
1. Small cell means high KI.
2. Large cells have low KI and divide.

Practice MCQs for NEET Biology Cell Cycle and Cell Division

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